Allo-antibodies in Pediatric Heart Transplantation

Protocol: 
CTOTC-04

CTOTC Alloantibodies in Cardiac Transplantation: interventions, outcomes and mechanisms

The purpose of this study is to determine the clinical outcomes of sensitized pediatric heart transplant recipients with a positive donor-specific cytotoxicity cross-match and to compare them with outcomes in nonsensitized heart transplant recipients.

Trial Website: https://clinicaltrials.gov/show/NCT01005316

Are you Eligible? (Inclusion Criteria)

Inclusion Criteria:

  • All participants listed for heart transplantation at participating CTOT-C study sites

Exclusion Criteria:

  • Listed for multiple organ transplant
  • Inability or unwillingness of the participant or parent/guardian to give a written informed consent or comply with the study protocol.
  • Condition or characteristic which in the opinion of the investigator makes the participant unlikely to complete at least one year of follow-up.
  • Current participation in other research studies that would, or might, interfere with the scientific integrity or safety of current study (e.g. by interference with immunosuppression management guidelines, study end-points, excessive blood draws or SAE evaluation)

Specialty Area(s)

Trial Location

NYP/Columbia
New York, NY 10032
United States