mFOLFIRINOX +/- Radiation

Protocol: 
AAAR3715

Phase II Preopertaive Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas

Are you Eligible? (Inclusion Criteria)

Inclusion Criteria:

  • Radiographic reading of borderline resectable disease
  • No prior chemo or radiation for pancreatic cancer

Exclusion Criteria:

  • Taking strong CYP3A4 inhibitors or inducers
  • Neuropathy grade 2 or greater
  • Homozygosity for UGAT1A1*28
  • Grade 3 or higher gastric ulcer disease within 28 days of study registration

Specialty Area(s)