Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients

Protocol: 
NCT02362646
Phase: 
II

Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients

The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ventricular assist device (LVAD) is safe. MPCs are normally present in human bone marrow and have been shown to increase the development of blood vessels and new heart muscle cells in the heart. In addition, this research is being done to test whether injecting the MPCs into the heart is effective in improving heart function.

Are you Eligible? (Inclusion Criteria)

Age 18 and over, scheduled to receive a left ventricular assist device (LVAD).

Specialty Area(s)

Trial Location

NewYork-Presbyterian/Columbia University Medical Center
Department of Surgery
New York, NY 10032
United States