Pancreatic Neuroendocrine Tumors

Pancreatic neuroendocrine tumors (PNET) arise from the hormone producing cells of the pancreas. Some of these tumors make hormones, the most common of which is an insulinoma. However, most PNET's are nonfunctional and do not produce hormones. Although these tumors are typically solid, occasionally they will become cystic. These "cysts" typically have a thick wall on imaging. The biologic behavior of PNET's is variable, and in patients of average fitness, they are generally removed by a variety of surgical techniques.