Physician’s Profile

Hiroo Takayama, MD, PhD

Top Doctor: 
Interim Surgical Director, Aortic Surgery Program NewYork-Presbyterian/Columbia University Medical Center, New York, NY
Co-Director, Hypertrophic Cardiomyopathy Center NewYork-Presbyterian/Columbia University Medical Center, New York, NY
Board Certificates: 
Thoracic Surgery
Cardiac Surgery
Cardiac Surgery
Heart Surgery
Heart Failure
Cardiogenic Shock
Extracorporeal Membrane Oxygenation (ECMO)
Hypertrophic Cardiomyopathy
Ischemic Heart Disease
Cardiac Valve Surgery
Aortic Surgery
Ventricular Assist Device Procedure
Heart Transplantation
Ventricular Septal Myotomy-Myectomy
2016 New York Magazine's Top Doctors
2012 Winner of Thoracic Surgery Residents Association Dwight C. McGoon Award
Heart failure
Cardiogenic shock
Minimally invasive aortic surgery
Brain protection in aortic arch surgery
Aortic valve repair

Dr. Hiroo Takayama is a heart surgeon. He graduated from University of Tokyo in 1996. To date, he has performed approximately 1,000 cardiac surgical procedures, of which 500 involved heart valve operations. He performs surgery at NewYork-Presbyterian/Columbia University Medical Center.

"I believe my greatest strength as a heart surgeon is that I have an expertise in operating on patients with complex aortic disease and/or significant heart failure.

These patients are often deemed inoperable elsewhere, and usually require a specific perioperative care to protect a previously damaged heart that may also require temporary circulatory support."

His cardiac specialties include: aortic surgery, surgery for heart failure and surgery for obstructive hypertrophic cardiomyopathy.

Dr. Takayama’s clinical interests relative to heart valve surgery include: valve-sparing aortic root surgery, aortic valve repair and mitral valve repair, heart failure surgery, ventricular support and cardiac transplantation.

Ota T, Takayama H, Khalpey Z, Naka Y. Reinforcement of HeartMate II bend relief connection: champagne bottle technique. Ann Thorac Surg. 2013 Apr;95(4):e107-8.
Nishimura T, Ota T, Takayama H, Naka Y. Subcostal to rib-cross incision for HeartMate II explantation: a case report. J Thorac Cardiovasc Surg. 2013 Jan;145(1):e16-7.
Akashi H, Kato TS, Takayama H, Naka Y, Farr M, Mancini D, Schulze PC. Outcome of patients with cardiac sarcoidosis undergoing cardiac transplantation-Single-center retrospective analysis. J Cardiol. 2012 Nov;60(5):407-10.
Javidfar J, Brodie D, Costa J, Miller J, Jurrado J, Lavelle M, Newmark A, Takayama H, Sonett JR, Bacchetta M. Subclavian artery cannulation for venoarterial extracorporeal membrane oxygenation. ASAIO J. 2012 Sep-Oct;58(5):494-8.
Takayama H, Chen JM, Jorde UP, Naka Y. Implantation technique of the CentriMag biventricular assist device allowing ambulatory rehabilitation. Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):110-1.
Kitada S, Kato TS, Thomas SS, Conwell SD, Russo C, Ditullio M, Farr M, Christian Schulze P, Uriel N, Jorde UP, Takayama H, Naka Y, Homma S, Mancini DM. Pre-operative Echocardiographic Features Associated With Persistent Mitral Regurgitation After Left Ven
Lanier GM, Orlanes K, Hayashi Y, Murphy J, Flannery M, Te-Frey R, Uriel N, Yuzefpolskaya M, Mancini DM, Naka Y, Takayama H, Jorde UP, Demmer RT, Colombo PC. Validity and Reliability of a Novel Slow Cuff-deflation System for Non-invasive Blood Pressure Mon
Lee R, Enter D, Lou X, Feins RH, Hicks GL, Gasparri M, Takayama H, Young JN, Calhoon JH, Crawford FA, Mokadam NA, Fann JI. The Joint Council on Thoracic Surgery Education coronary artery assessment tool has high interrater reliability. Ann Thorac Surg. 20
Kato TS, Cheema FH, Yang J, Kawano Y, Takayama H, Naka Y, Farr M, Lederer DJ, Baldwin MR, Jin Z, Homma S, Mancini DM, Schulze PC. Preoperative serum albumin levels predict 1-year postoperative survival of patients undergoing heart transplantation. Circ He
Garan AR, Yuzefpolskaya M, Colombo PC, Morrow JP, Te-Frey R, Dano D, Takayama H, Naka Y, Garan H, Jorde UP, Uriel N. Ventricular arrhythmias and implantable cardioverter-defibrillator therapy in patients with continuous-flow left ventricular assist device
Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk ca
Uriel N, Jorde UP, Woo Pak S, Jiang J, Clerkin K, Takayama H, Naka Y, Christian Schulze P, Mancini DM. Impact of long term left ventricular assist device therapy on donor allocation in cardiac transplantation. J Heart Lung Transplant. 2013 Feb;32(2):188-9
Yuzefpolskaya M, Uriel N, Chow DS, Restaino SW, Mancini DM, Flannery M, Te-Frey R, Chichetti J, Ota T, Kim H, Dano DD, Pearson GD, Takayama H, Naka Y, Jorde UP. Prevalence and timing of bend relief disconnection in patients supported by the late version H
Soni LK, Cedola SR, Cogan J, Jiang J, Yang J, Takayama H, Argenziano M. Right atrial lesions do not improve the efficacy of a complete left atrial lesion set in the surgical treatment of atrial fibrillation, but they do increase procedural morbidity. J Th
Takayama H, Truby L, Koekort M, Uriel N, Colombo P, Mancini DM, Jorde UP, Naka Y. Clinical outcome of mechanical circulatory support for refractory cardiogenic shock in the current era. J Heart Lung Transplant. 2013 Jan;32(1):106-11.
Wu C, Kato TS, Pronschinske K, Qiu S, Naka Y, Takayama H, Schulze-Späte U, Cremers S, Shane E, Mancini D, Schulze PC. Dynamics of bone turnover markers in patients with heart failure and following haemodynamic improvement through ventricular assist device
Uriel N, Morrison KA, Garan AR, Kato TS, Yuzefpolskaya M, Latif F, Restaino SW, Mancini DM, Flannery M, Takayama H, John R, Colombo PC, Naka Y, Jorde UP. Development of a Novel Echocardiography Ramp Test for Speed Optimization and Diagnosis of Device Thro
Goda A, Takayama H, Pak SW, Uriel N, Mancini D, Naka Y, Jorde UP. Aortic valve procedures at the time of ventricular assist device placement. Ann Thorac Surg. 2011 Mar;91(3):750-4.
Goda A, Takayama H, Koeckert M, Pak SW, Sutton EM, Cohen S, Uriel N, Jorde U, Mancini D, Naka Y. Use of Ventricular Assist Devices in Patients with Mitral Valve Prostheses. J Card Surg. 2011 May;26(3):334-7.
Munir MB, Jiang J, Mehdi MJ, Takayama H, Cheema FH. Letter to the editor: A Novel Subcutaneous Counterpulsation Device: Acute Hemodynamic Efficacy During Pharmacologically Induced Hypertension, Hypotension, and Heart Failure. Art Organs. 2011 Jan;35(1):92
Hong KN, Iribarne A, Yang J, Ramlawi B, Takayama H, Naka Y, Russo MJ. Do posttransplant outcomes differ in heart transplant recipients bridged with continuous and pulsatile flow left ventricular assist devices? Ann Thorac Surg. 2011 Jun;91(6):1899-906.
Sims DB, Uriel N, González-Costello J, Deng MC, Restaino SW, Farr MA, Takayama H, Mancini DM, Naka Y, Jorde UP. Human immunodeficiency virus infection and left ventricular assist devices: A case series. J Heart Lung Transplant. 2011 Apr 22.
Ben-Gal Y, Stone GW, Smith CR, Williams MR, Weisz G, Stewart AS, Takayama H, Genereux P, Argenziano M. On-pump versus off-pump surgical revascularization in patients with acute coronary syndromes: Analysis from the Acute Catheterization and Urgent Interve
Javidfar J, Brodie D, Takayama H, Mongero L, Zwischenberger J, Sonett J, Bacchetta M. Safe transport of critically ill adult patients on extracorporeal membrane oxygenation support to a regional extracorporeal membrane oxygenation center. ASAIO J. 2011 Se
Sims DB, Takayama H, Uriel N, Gillam LD, Naka Y, Jorde UP. Ventricular assist device-associated thrombus. Circulation. 2011 Aug 16;124(7):e197-8.
Kato TS, Chokshi A, Singh P, Khawaja T, Cheema F, Akashi H, Shahzad K, Iwata S, Homma S, Takayama H, Naka Y, Jorde U, Farr M, Mancini DM, Schulze PC. Effects of Continuous- Versus Pulsatile-Flow Left Ventricular Assist Devices on Myocardial Unloading and
Takayama H, Naka Y, Kodali SK, Vincent JA, Addonizio LJ, Jorde UP, Williams MR. A novel approach to percutaneous right-ventricular mechanical support. Eur J Cardiothorac Surg. 2011 Jul 5.
Hong KN, Iribarne A, Worku B, Takayama H, Gelijns AC, Naka Y, Jeevanandam V, Russo MJ. Who is the high-risk recipient? Predicting mortality after heart transplant using pretransplant donor and recipient risk factors. Ann Thorac Surg. 2011 Aug;92(2):520-7
Wei B, Takayama H, Bacchetta MD. Pulmonary lobectomy in a patient with a left ventricular assist device. Ann Thorac Surg. 2009 Jun;87(6):1934-6.
Takayama H, Smith CR, Bowdish ME, Stewart AS. Open Distal Anastomosis in Aortic Root Replacement using Axillary Cannulation and Moderate Hypothermia. J Thorac Cardiovasc Surg 2009 Jun; 137(6): 1450-3.
Tabata M, Takayama H, Bowdish ME, Smith CR, Stewart AS. Modified Bentall operation with bioprosthetic valved conduit. Ann Thorac Surg Jun; 87(6): 1969-70.
Takayama H. The role of PA and NP in cardiac surgery in US: report from Columbia University Medical Center Nippon Geka Gakkai Zasshi. 2009 Jan;110(1):52-4.
Takayama H. What is Physician Assistant. Nikkei Medical. 2008 December.
Takayama H, Salerno CT, Aldea GS, Verrier ED. Characteristics of Extracoronary Vascular Disease in Heart Transplant Recipient. J Card Surg. 2008 Sep-Oct;23(5):459-63.
Takayama H, Soltow LO, Aldea GS. Differential Expression in Markers for Thrombin, Platelet Activation and Inflammation in Cell Saver versus Systemic Blood in Patients Undergoing On-Pump CABG. J Cardiothorac Vasc Anesth. J Cardiothorac Vasc Anesth. 2007 Au
Takayama H, Soltow LO, Chandler WL, Vocelka CR, Aldea GS. Does the Type of Surgery Effect Systemic Response Following Cardiopulmonary Bypass? J Card Surg. 2007 Jul-Aug;22(4):307-13.
Oelschlager BK, Namkung J, Takayama H. Is This Achalasia or Pseudoachanlasia? Contemporary Surgery. 2007 May; online publication.
Takayama H, Nathens AB, Aldea GS, Fishbein DP, Verrier ED, Salerno CT. is pre-transplant vascular disease a risk factor for mortality and morbidity after heart transplant? Eur J Cardiothorac Surg. 2007 Mar;31(3):457-61.
Cobey FC, Takayama H. Images in clinical medicine. Contraceptive failure. N Engl J Med. 2007 Jan 25;356(4):397.
Takayama H, Sinanan MN, Fishbein DP, Aldea GS, Verrier ED, Salerno CT. Expectant Management is Safe for Cholelithiasis after Heart Transplant. J Heart Lung Transplant. 2006 May;25(5):539-43.
Takayama H, Grinsell R, Brock D, Foy H, Pellegrini C, Horvath K. Is it Appropriate to Use Core Clerkship Grades in the Selection of Residents? Curr Surg. 2006 Nov-Dec;63(6):391-6.
Takayama H, Leone RJ, Aldea GS, Fishbein DP, Verrier ED, Salerno CT. Delayed Sternal Closure after Heart Transplantation. Tex Heart Inst J. 2006;33(3):306-9.
Shimamoto A, Chong AJ, Yada M, Shomura S, Takayama H, Fleisig AJ, Agnew ML, Hampton CR, Rothnie CL, Spring DJ, Pohlman TH, Shimpo H, Verrier ED. Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injury. Circulatio
Takayama H, Aldea GS, Verrier ED, Salerno CT, Levy WC, Fishbein DP. Successful management of asystole with an isolated left ventricular assist device. J Heart Lung Transplant. 2006 Apr;25(4):490-2.
Kitahori K, Takamoto S, Takayama H, Suematsu Y, Ono M, Motomura N, Morota T, Takeuchi K. A novel protocol of retrograde cerebral perfusion with intermittent pressure augmentation for brain protection. J Thorac Cardiovasc Surg. 2005 Aug;130(2):363-70.
Takayama H, Chikada M, Takamoto S, Sekiguchi A, Ishizawa A. Pulmonary artery banding still has an important role in the treatmant of congenital heart disease: reply. Ann Thorac Surg. 2005 Apr;79(4):1463-4.
Yada M, Shimamoto A, Hampton CR, Chong AJ, Takayama H, Rothnie CL, Spring DJ, Shimpo H, Yada I, Pohlman TH, Verrier ED. FR167653 diminishes infarct size in a murine model of myocardial ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2004 Oct;128(4)
Chong AJ, Shimamoto A, Hampton CR, Takayama H, Spring DJ, Rothnie CL, Yada M, Pohlman TH, Verrier ED. Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart. J Thorac Cardiovasc Surg. 2004 Aug;128(2):170-9.
Takayama H, Otsuka T, Kubota H, Shibata K, Kitamura T, Takamoto S. Pseudoaneurysm developed after aortic root homograft implantation. Jpn J Thorac Cardiovasc Surg. 2004 Mar;52(3):158-60.
Takayama H, Hamner CE, Caccitolo JA, Hisamochi K, Pearson PJ, Schaff HV. A novel antioxidant, EPC-K1, stimulates endothelial nitric oxide production and scavenges hydroxyl radicals. Circ J. 2003 Dec;67(12):1046-52.
Kitamura T, Motomura N, Ohtsuka T, Shibata K, Takayama H, Kotsuka Y, Takamoto S. Aortopulmonary fistula in pseudoaneurysm after ascending aortic surgery. J Thorac Cardiovasc Surg. 2003 Sep;126(3):904-5.
Suematsu Y, Takamoto S, Kaneko Y, Ohtsuka T, Takayama H, Kotsuka Y, Murakami A. Beating atrial septal defect closure monitored by epicardial real-time three-dimensional echocardiography without cardiopulmonary bypass. Circulation. 2003 107(5):785-90.
Takayama H, Morota T, Motomura N, Ono M, Kotsuka Y, Takamoto S. Rupture of A Small Fusiform Thoracic Aortic Aneurysm. Jpn J Thorac Cardiovasc Surg. 2003 51: 32-33.
Murakami A, Takamoto S, Takaoka T, Kobayashi J, Maeda K, Takayama H, Motomura N, Murakawa T, Ono M. Saphenous vein homograft containing a valve as a right ventricle-pulmonary artery conduit in the modified Norwood operation. J Thorac Cardiovasc Surg 2002
Murakami A, Maeda K, Takayama H, Takaoka T, Kobayashi J, Takamoto S. Successful treatment with intraluminal fibrinogen injection of serous leakage from a polytetrafluoroethylene Blalock-Taussig shunt. J Thorac Cardiovasc Surg 2002 124: 1037-1038.
Takayama H, Sekiguchi A, Chikada M, Noma M, Ishizawa A, Takamoto S. Mortality of Pulmonary Artery Banding in the Current Era. Ann Thorac Surg. 2002 74: 1219-24.
Chikada M, Sekiguchi A, Takayama H, Tonari K, Saito A, and Ishizawa A. Usefulness of pulsatile bidirectional cavopulmonary shunt in high-risk fontan patients. Ann. Thorac. Surg. 2002 74: 971-2.
Chikada M, Sekiguchi A, Oho S, Miyamoto T, Ishida R, Takayama H, Ishizawa A. Dilatable banding of a Blalock-Taussig shunt. Ann Thorac Surg. 2002;74:253-5.
Takayama H, Sekiguchi A, Chikada M, Noma M, Ishida R. Aortopulmonary window due to balloon angioplasty after arterial switch operation. Ann Thorac Surg. 2002;73:659-61.
Hirata Y, Ohtsuka T, Motomura N, Kubota H, Takayama H, Kitahori K, Kotsuka Y, Takamoto S. Three Cases of Coronary Artery Bypass Grafting with Vein Graft Anastomosed Proximally to the Axillary Artery and Placed through the Chest Cavity. Jpn Circ J; 65: 609
Takayama H, Sekiguchi A, Chikada M. 1995. Pulmonary atresia with intact ventricular septum: long-term results of "one and a half ventricular repair". Updated in 2001. Ann Thorac Surg. 2001;72:2178-9.
Takayama H, Ohba N, Ori T, Takagi M, Nakagami K, Iseki J, Toyama K, Ito K, Muro H. Three Successfully resected cases of hepatocellular carcinoma with bile duct thrombi. Jpn J Gastroenterol Surg. 2000; 33: 1910-4.
Ohba N, Tohyama K, Iseki J, Nakagami K, Takagi K, Ori T, Watanabe M, Sato Y, Takayama H, Hiramatsu Y, Ito K. Surgical Resection of An Epithelioid Hemangioendothelioma with Peritoneal Dissemination. Jpn J Gastroenterol Surg. 1999.