Isaac George, MD
About Isaac George, MD:
Isaac George, MD, joined Columbia University Medical Center/NewYork-Presbyterian in 2001 as a resident in general surgery after graduating from Duke University School of Medicine. He received a B.S. in Mechanical Engineering from the Massachusetts Institute of Technology in 1997. He completed a fellowship in cardiothoracic surgery in 2011 and a fellowship in interventional cardiology in 2012. He is an Associate Professor of Surgery and Medicine, the Surgical Director of Structural Heart Disease at NewYork-Presbyterian Hospital, the Surgical Director of the Structural Heart and Valve Center, and Co-Director of the Mitral and Tricuspid Center.
Dr. George is board certified in thoracic (cardiac) surgery. His practice includes all types of open and reoperative adult cardiac surgery, including aortic, mitral, and tricuspid valve surgery, aortic aneurysm repair, coronary bypass grafting, and robotic surgery. He specializes in minimally invasive mitral valve repair. He performs 150 to 200 open heart surgeries each year and is the highest-volume heart surgeon in New York State. His annual surgical mortality rate is approximately 1.5%.
Dr. George is trained in both cardiac surgery and interventional cardiology. His practice includes transcatheter aortic valve replacement (TAVR), transcatheter mitral valve repair (MitraClip), transcatheter mitral and tricuspid valve replacement, and surgical TAVR explantation. He performs around 800 transcatheter procedures each year and has performed nearly 8,000 TAVR procedures.
He is a Primary Investigator for multiple national surgical and transcatheter trials and is involved in research related to aortic stenosis, aortic insufficiency, bicuspid aortic valves, mitral regurgitation, tricuspid regurgitation, and heart failure. His research includes both clinical and benchtop studies with translational applications.
Hear Dr. George talk about the one-year clinical results of the novel polymeric leaflet TRIA valve for patients undergoing surgical mitral valve replacement: https://www.instagram.com/reel/DL8SYzdsIE5/
Expertise:
Honors:
2019: American Association of Thoracic Surgeons Biology Cup Winner - Best Presentation
2017: Columbia University Deparment of Surgery - Junior Faculty Research Grant
2016: American Association of Thoracic Surgeons Graham Surgical Investigator Award
2015: Columbia University Department of Surgery - Kenneth Forde Research Award
2008: Blakemore Prize – Best Resident Research Award, Columbia University College of Physicians and Surgeons
2007: Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons
2006: Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons
2004: New Era Cardiac Surgery Conference Scholarship
1995: Pi Tau Sigma, Mechanical Engineering Honor Society
Interests:
Appointments:
Education:
New Patients:
Locations
Primary Locations:
CUIMC/Milstein Hospital Building
177 Ft. Washington Avenue
New York, NY 10032
- For new and current patient appointments, call:
- 212-305-4134
Other Locations:
ColumbiaDoctors - 15 North Broadway
15 North Broadway
Suite C
White Plains, NY 10601
ColumbiaDoctors - Glenpointe
300 Frank W Burr Blvd
Suite 130
Teaneck, NJ 07666
Insurances:
Please contact the doctor's office directly to verify that your particular insurance is accepted.
Publications:
Nazif TM, Cahill TJ, Daniels D, McCabe J, Reisman M, Chakravarty T, Makkar R, Krishnaswamy A, Kapadia S, Chehab B, Wang J, Spies C, Rodriguez E, Hahn RT, Leon MB, George I. Real-World Experience with the Sapien 3 Ultra transcatheter heart valve: a propensity matched analysis from the United States. (submitted)
Brener MI, Old A, Nemeth S, Kurlansky P, Nazif TM, Vahl TP, Khalique O, Hamid NB, Patel A, Ng V, Chen S, Cahill TJ, Rahim HM, Hahn RT, Bapat V, Ahmed MI, Leon MB, Kodali S, Eudailey KW, George I. Suprasternal Versus Transfemoral Access for Transcatheter Aortic Valve Replacement: Insights from a Propensity Score Matched Analysis. (submitted)
Shahim B, Redfors B, Chen S, Dahlen T, Lindman B, Nazif T, Kapadia S, Gertz Z, Crawly A, Li D, Thourani V, Kodali S, Zajarias A, Babaliaros V, Guyton R, Elmariah S, Herrmann H, Mack M, Smith CR, Leon MB, George I. Prognostic Value of Serial Neutrophil-to-Lymphocyte Ratio in Patients Undergoing Transcatheter or Surgical Aortic Valve Replacement-The PARTNER I-II Trials and Registries. (submitted)
Castillero E, Howsmon B, Rego BV, Keeney S, Driesbaugh KH, Xue Y, Camillo C, George I, Gorman RC, Gorman JH, Sacks MS, Levy RJ, Ferrari G. Altered Responsiveness to Transforming Growth Factor/Bone Morphogenic Protein Signaling and Increased CD45% Fibrocyte Presence in Mitral Valves are Distinctive of Ischemic Mitral Regurgitation After Myocardial Infarction. (submitted)
Shahim B, Malasrie C, George I, Thourani VH, Biviano AB, Russo M, Brown DL, Babaliaros V, Guyton RA, Kodali SK, Nazif TM, McCabe JM, Williams M, Genereux P, Lu M, Yu X, Alu M, Webb JG, Mack MJ, Leon MB, Kosmidou I. Impact of Preexisting Atrial Fibrillation on Clinical Outcomes After Transcatheter or Surgical Aortic Valve Replacement for Severe Aortic Stenosis: an Analysis from the PARTNER 3 Trial. (submitted)
Sadri S, Loeb GJ, Grinspoon A, Elvezio C, Sun SH, Ng VG, Khalique O, Moses JW, Patel AJ, George I, Hahn RT, Nazif TM, Leon MB, Kirtane AJ, Kodali SK, Feiner SK, Vahl TP. Towards a Virtual Future: Augmented Reality Guidance for Cerebral Embolic Protection during TAVR. (submitted)
Yamabe T, Pearsall CA, Zhao Y, Kurlansky P, Bethancourt CN, Nitta S, George I, Smith CR, Takayama H. Incidence, Cause, and Outcome of Reintervention after Aortic Root Replacement. (submitted)
Fam NP, von Bardeleban RS, Hensy M, Kodali SK, Smith RL, Hausleiter J, Ong G, Boone R, Ruf T, George I, Szerlip M, Nabauer M, Ali FM, Moss R, Bapat V, Schnitzler K, Kriedel F, Ye J, Deva DP, Mack MJ, Grayburn PA, Peterson MD, Leon MB, Hahn RT, Webb JG. Transfemoral Transcathetere Tricuspid Valve Replacement with the EVOQUE System for Severe Tricuspid Regurgitation: A Multicenter, Observational, First-in-Human Experience. (Accepted-JACC Cardiovasc Int)
Von Ballmoos MC, Forrest JK, Williams MR, Mangi AA, Kleiman N, Yakubov SJ, Watson D, Kodali S, George I, Tadros P, Zorn GL, Brown J, Kipperman R, Oh JK, Qiao H, Reardon MJ. Three-Year Outcomes with a Contemporary Self-Expanding Transcatheter Valve from the Evolut PRO US Clinical Sudy. (submitted)
Yamabe T, Zhao Y, Kurlansky PA, Nitta S, Kelebeyev S, Bethancourt CN, George I, Smith CR, Takayama H. Chronic Kidney Disease stratifies short- and long-term outcomes after aortic root surgery. (submitted)
Dallan, LA, Forrest JK, Reardon MJ, Szeto WY, George I, Kodali S, Kleiman NS, Yakubo SJ, Grubb KJ, Liu F, Baeza C, Attizzani GF. Transcatheter Aortic Valve Replacement with Self-Expandable Supra-Annular Valves for Failed Surgical Bioprostheses: Insights From TVT-Registry. (submitted)
Gupta A, Mori M, Wang Y, Vahl T, Nazif T, Kirtane AJ, George I, Kodali S, Giersson A, Leon MB, Krumholz HM. Sex- and Race-based differences in Transcatheter and Surgical Aortic Valve Replacement Among Older Adults in the United States, 2012-2017. (submitted)