Profile image of Julia J Wattacheril, MD, MPH

Julia J Wattacheril, MD, MPH

Director of the Nonalcoholic Fatty Liver Disease Program
Attending, New York - Presbyterian Hospital
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Expertise:

Chronic Liver Disease
Gastroenterology
Hereditary Liver Disease
Liver Disease
Liver Transplantation
Non-Alcoholic Fatty Liver Disease
Non-Alcoholic Steatohepatitis
Transplant Hepatology

About:

Dr. Wattacheril's clinical specialties include all aspects of transplant hepatology, general hepatology and gastroenterology with emphasis on metabolic liver disease and obesity. She specializes in nonalcoholic fatty liver disease as well as all forms of hepatitis, chronic liver disease, and liver cancer in addition to liver transplantation. Her research interests include hepatic steatosis, insulin resistance, gut hormones and metabolic liver disease in adults. Her current research concentrates on the relationship between proteins and lipids that differentiate steatosis from steatohepatitis using an integrated omics approach.

Visit The Center for Liver Disease and Transplantation at columbiasurgery.org/liver

Honors:

2003 Alpha Omega Alpha

2000 Glasgow-Rubin Achievement Citation recipient, American Medical Women’s Association

Interests:

Non-alcoholic fatty liver disease (including non-alcoholic steatohepatitis)
Insulin Resistance
Hepatocellular carcinoma
Metabolic liver diseases
OMICs
Lipid metabolism
Transplant hepatology
Body Composition
Algorithm development and machine learning methods for disease phenotyping

Publications:

*Pomenti S, Gandle C, Abu Sbeih H, Phipps M, Livanos A, Guo A, Yeh J, Burney H, Liu H, Dakhoul L, Kettler C, Gawrieh S, deLemos A, Scanga A, Chalasani N, Miller E, Wattacheril J. Hepatocellular Carcinoma in Hispanic Patients: Trends and Outcomes in a Large United States Cohort. Hep Communications2020: doi.org/10.1002/hep4.1575

*Phipps M, Livanos A, Guo A, Pomenti S, Yeh J, Dakhoul L, Burney H, Kettler C, Liu H, Miller E, GawriehS, deLemos A, Scanga A, Chalasani N, Wattacheril J. Gender Matters: Characteristics of Hepatocellular Carcinoma in Women from a Large, Multicenter Study in the United States. Am J Gastroenterol2020: doi: 10.14309/ajg.0000000000000643.

deLemos, A, Patel M, Gawrieh S, Burney H, Dakhoul L, Miller E, Scanga A, Kettler C, Liu H, Roche P, Wattacheril J, Chalasani N. Distinctive Features and Outcomes of Hepatocellular Carcinoma in Patients with Alcohol-Related Liver Disease: A US Multicenter Study. Clin Transl Gastroenterol2020: doi: 10.14309/ctg.0000000000000139.

Siddiqui MS, Van Natta ML, Connelly MA, Vuppalanchi R, Neuschwander-Tetri BA, Tonascia J, Guy C, Loomba R, Dasarathy S, Wattacheril J, Chalasani N, Sanyal AJ; NASH-CRN. Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis. J Hepatology2020 doi: 10/1016/j.hep.2019.10.006

*Gawrieh S, Dakhoul L, Miller E, Scanga A, deLemos A, Kettler C, Burney H, Liu H, Abu-Sbeih H, Chalasani N, Wattacheril J. Characteristics, Aetiologies and Trends of Hepatocellular Carcinoma in Patients without Cirrhosis: A United States Multicenter Study. Alimentary Pharmacology and Therapeutics.2019 doi.org/10.1111/apt15464

Wattacheril J, Shea PR, Mohammad S, Behlin C, Aggarwal V, Wilson LA, Yates KP, Ito J, Fishbein M, Stong N, Lavine JE, Goldstein DB. Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson Disease. Cold Spring Harb Mol Case Stud.2018 Oct 1.doi: 0.1101/mcs.a003087

Wattacheril J, Lavine JE, Chalasani NP, Guo X, Kwon S, Schwimmer J, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Tonascia J, Rotter JI. Genome Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. J Pediatr. 2017 Nov. doi:10.1016/j.jpeds.2017.08.004

Wattacheril J, Rose, K.L., Hill, S., Lanciault, C., Murray, C.R., Washington, K., Williams, B., English, W., Spann, M., Clements, R., Abumrad, N., and Flynn, C.R.(2017) NAFLD Phosphoproteomics: A Functional Piece of the Precision Puzzle. Hepatol Res, doi:10.1111/hepr.12885.

Corey KE, Gawrieh S, deLemosAS, Zheng H, Scanga AE, Haglund JW, Sanchez J, Danford CJ, Comerford M, BossiK, Munir S, Chalasani N, Wattacheril J. Risk factors for hepatocellular carcinoma in cirrhosis due to nonalcoholic fatty liver disease: A multicenter, case-control study. World J Hepatol 2017; 9(7): 385-390

Guo Y, Xiong Y, Sheng Q, Zhao S, Wattacheril J, Flynn CR. A micro-RNA expression signature for human NAFLD progression. J Gastroenterol. 2016 Feb 13.

Garcia A, Kasim N, Gonzalez, R, Antoun J, Eckert E, Marks P, Wattacheril J, Abumrad N, Tamboli R, Walle T, Dunn J, Flynn CR. Lipoprotein Profiles in Class III Obese Caucasian and African American Women with Nonalcoholic Fatty Liver Disease. PLoS One.2015 Nov 23;10(11):e0142676. doi: 10.1371/journal.pone.0142676

Sharifnia T, Antoun J, Suarez G, Wattacheril J, Wilson K, Peek RM, Abumrad N, and Flynn CF. Hepatic TLR4 Signaling in Obese NAFLD. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 15;309(4):G270-8. doi: 10.1152/ajpgi.00304.2014