Physician’s Profile

Mercedes Martinez, MD

Top Doctor: 
1
Medical Director, Intestinal Transplant Program, Center for Liver Disease and Abdominal Organ Transplantation
Clinical Director, Human Studies Core, Columbia Center for Translation Immunology
Associate Program Director, Liver Transplant Hepatology Fellowship
Affiliations: 
NewYork-Presbyterian/Columbia
NewYork-Presbyterian/Morgan Stanley Children's Hospital
Board Certificates: 
Pediatric Transplant Hepatology
Pediatric Gastroenterology
Pediatrics
Expertise: 
Liver Transplantation
Liver Tumors
Pediatric Liver Cancer
Pediatric Liver Disease-Acute
Pediatric Liver Disease-Chronic
Short Bowel Syndrome
Gastrointestinal Bleeding
Gastrointestinal ERCP
Gastrointestinal Tumors
Hepatic Disorders
Hepatitis
Hepatitis C
Hepatobiliary Pancreas Disease
Hepatology
Intestinal Atresia
Intestinal Transplant
Liver Transplant, Pediatric
Liver Disease In Children
Pediatric Liver Transplant
Transplant Surgery, Pediatric
About: 

Mercedes Martinez, MD, is an Associate Professor of Pediatrics and the Medical Director for the Intestinal Transplant Program at the Center for Liver Disease and Abdominal Organ Transplantation. She provides state-of-the-art care for children with a multitude of liver and intestinal issues, including children with liver and intestinal failure that require transplantation, children with intestinal failure, and for those with intestinal failure associated liver disease. Her research interests include liver tumors in children, autoimmune liver diseases, metabolic disorders, nutritional deficiencies associated with liver diseases, and intestinal failure.

Publications: 
(Underline indicates mentees, *indicates senior authorship) 
  Peer-Reviewed Articles Perito ER, MartinezM,TurmelleY, Mason K, Spain KM, BucuvalasJC, FengS. Post-transplant Biopsy Risk among Stable Long-term Pediatric Liver Transplant Recipients: 451 Percutaneous Biopsies from Two Multi-center immunosuppression Withdrawal Trials. Accepted to AJT Chuadhry S, Kato Y, Weiner J, Alonso-Guallart P, Baker S, Woodland DC III, Lefkowitch JH, Y Duran-Struuck R, Sondermeijer HP, Zitsman J, Sears M, Wu A, Karolewski B, Houck PJ, Martinez M, Kato T, Sykes K, Griesemer A. Transient mixed chimerism for the induction of tolerance in nonhuman primates: Comparison of results between liver and kidney transplants. Nature scientific reports Vittorio J, Martinez M, Lobritto SJ. Partial splenic embolization is safe and effective alternative in the management of portal hypertension in Children. Accepted JPGN FuJ, ZuberJ, Martinez M, ShontsB, ObradovicA, Wang H, Lau SP, Xia A, WaffarnEE, SavageTM, SimpsonMT, YangS, GuoX, MironM, SendaT, Rogers K, RahmanA, Ho SH, Shen Y, Griesemer A, FarberD, Kato T, Sykes M. Human intestinalAllografts Contain FunctionalHematopoietic Stem and Progenitor Cellsthat are Maintained by a Circulating Pool. Cell Stem Cell. 2018 Nov 21. PMID: 30503142 Deneau M, El-Matary W, Valentino P, Abdou R, Alqoaer K, Amin M, Amir A, Auth M, Bazerbachi F, Broderick A, Chan A, Cotter J, Doan S, El-Youssef M, Ferrari F, Furuya K, Gottrand F, Gottrand M, Gupta N, Homan M, Kamath B, Kim KM, Kolho K, Konidari A, Koot B, Iorio R, Ledder O, Mack C, Martinez M,Miloh T, Mohan P, OCathain N, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Vos M, Woynarowski M, Yap J, Jensen MK. GGT improvement predict survival in pediatric primary sclerosing cholangitis regardless of ursodeoxycholic acid use.  Hepatology Communications. 2018 Sep 25. PMID: 30411083 Goldner D,Vittorio J, Barrios DM, McGuire J, Brodlie S,Brown J, Lobritto S, *Martinez M. BoneFractures in Children with Cholestatic Liver Disease May Mimic those seen in Child Abuse. Accepted Pediatric Emergency Care.  Arterbery A, Yao J, Ling A, Avitzur Y, Martinez M,Lobritto S, Deng Y, Geliang G, Mehta S, Wang G, Knight J, PhD5, Ekong UD. Inflammasome priming mediated via toll-like receptors 2 and 4 indices TH1-like Treg in the DeNovo autoimmune hepatitis. Frontiers in immunology. 2018 Jul 19;PMID: 30072988 PMCID: PMC6060440 Ravella S, Liou P, Velassco M, Harrison A, Kato T, *MartinezM. Nutritional challenges in patients after intestinal auto-transplantation and ex-vivo surgery. JPEN. 2018 Jul 20.  PMID: 30028516 Elnaggar A, Griesemer A., Bentley-Hibbert S, Brown RS Jr., Lobritto S, Martinez M, Kato T, Emond J.Liver Atrophy and Regeneration in Non-Cirrhotic Portal Vein Thrombosis: Effect of Surgical Shunts. Liver Transpl.2018 Jan 29. PMID: 29377486  Chaudhry S, Bentley-Hibbert  S, Stern J, Lobritto S, Martinez M, Vitorrio J, Halazun KJ, Lee HT, Emond J, Kato T, Samstein B, Griesemer A. Growth of Liver Allografts Over Time in Pediatric Transplant Recipients. Pediatr Transplant. 2018 Jan 15. doi: 10.1111/petr.13104. PMID: 29334158 Przybyzsewski E, Verna E, Lobritto S, Martinez M, Vittorio J, Fox AN, Samstein B, Kato T, Griesemer A, Emond J. Durable Clinical and Immunologic Advantage of Living Donor Liver Transplantation in Children. Transplantation.2018 Jan 23. PMID: 29369249  Kato Y, MD, Griesemer AD, Wu A, Sondermeijer H, Weiner J, Duran-Struuck R, Martinez M, Slate A, Romanov A, Lefkowitch JH, Sykes M, Kato T. Novel H-shunt Veno-venous Bypass for Liver Transplantation in Cynomolgus Macaques. Comparative Medicine. 2017 Oct 1; 67, (5). PMID: 28935006 Ekong UD, McKiernan P, Martinez M, Lobritto S, Kelly D, Ng VL, Alonso EM, Avitzur Y. Long-Term Outcomes of De Novo Autoimmune Hepatitis in Pediatric Liver Transplant Recipients. Pediatric Transplantation. 2017 May 29. doi: 10.1111/petr.12945. PMID: 28556542 Deneau M, El-Matary W, Valentino P, Abdou R, Alqoaer K, Amin M, Amir A, Auth M, Bazerbachi F, Broderick A, Chan A, Cotter J, Doan S, El-Youssef M, Ferrari F, Furuya K, Gottrand F, Gottrand M, Gupta N, Homan M, Kamath B, Kim KM, Kolho K, Konidari A, Koot B, Iorio R, Ledder O, Mack C, Martinez M,Miloh T, Mohan P, OCathain N, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Vos M, Woynarowski M, Yap J, Jensen MK. The natural history of primary sclerosing cholangitis in 781 children: an international, multicenter collaboration. Hepatology. 2017 April 8. PMID: 28390159 Weiner J, Zuber J, Shonts B, Yang S, Fu J, Martinez M, FarberD, Kato T, Sykes M. Long-term persistence of innate lymphoid cells in the gut after intestinal transplantation. Transplantation. 2016. Dec 8. PMID: 27941430 PMCID: PMC5462871 Duran-Struuck R, Sondermeijer HP, Bühler L, Zitsman J, Kato Y, Wu A, Alonso-Guallart P, McMurchy A, Woodland D, Griesemer A, Martinez M, Boskovic S, Kawai T, Cosimi AB, Wuu AA, Slate A, Baker S, Tokarz R, d’Agati V, Hammer S, Pereira M, Lipkin I, Wekerle T, Levings M, Sykes K.  Effect of ex-vivo expanded recipient regulatory T-cells on hematopoietic chimerism and kidney allograft tolerance across MHC barriers in Cynomolgus macaques. Transplantation 2017. Feb. 01(2):274-283. PMID: 27846155. PMCID: PMC5263090 Zuber J, Shonts B, Lau SP, ObradovicA, Fu J,Yang S, LambertM, Coley S, Weiner J, Thome J, DeWolf S,FarberD, Shen Y, Caillat-ZucmanS, Bhagat G, Griesemer A, Martinez M, Kato T, Sykes M. Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome. Sci Immunol.2016 Oct;1(4). pii: eaah3732.doi:10.1126/sciimmunol.aah3732. Epub 2016 Oct 7. PMID: 28239678 PMCID: PMC5323244 Geller J, Kasahara M, Martinez M, Soresina A, Endrikat J. Safety and efficacy of of Gadoxetate disodium Enhanced Liver MRI in Pediatric Patients aged ˃2 Months to