Risk factors for pancreatic cancer may include family members who have been diagnosed with PC, as well as health and lifestyle factors, many of which are currently under study. These may include age, ethnicity, smoking, diabetes, chronic pancreatitis, weight and genetics. Our program focuses on, but is not limited to, identifying and caring for individuals who have a family history of pancreatic cancer.
The effectiveness of our screening for pancreatic cancer has revealed some encouraging results. Our screening program helps determine whether risk factors are present, while addressing the patient as a whole.
In our published experience, we followed 51 patients from 2005-2008. 24 patients had genetic testing, of which 7 patients tested positive for BRCA mutations. One patient had resectable pancreatic cancer on initial screening; two patients chose to undergo prophylactic total abdominal hysterectomy and bilateral salpingo-oophorectomy given their positive BRCA mutation status — of these, one had ovarian papillary serous adenocarcinoma and one with tubal intraepithelial carcinoma. On follow-up, we have detected new abnormalities in the pancreas in 7 of 29 patients that did not have surgery after their initial visit and have completed 18 months of screening- none of which have required surgery, but are instead being followed closely; in the patients that did undergo surgery initially, we have found new abnormalities in 2 of 3 patients. Thus, we believe that it may be possible for patients at moderate or high risk to have follow-up screening approximately every year, while patients who have already undergone surgery may benefit from interval screening at 6 months.
Request an Appointment or call us at 212-305-9467.