Randomized controlled trial of Vitamin D Repletion Regimens in Primary Hyperparathyroidism

Protocol: 
AAAF1797

Randomized controlled trial of Vitamin D Repletion Regimens in Primary Hyperparathyroidism

Primary hyperparathyroidism (PHPT) is a condition characterized by overactivity of the parathyroid glands leading to elevated parathyroid hormone and blood calcium levels. Other affected organs include the skeleton (calcium loss leads to a "weakening" of the skeleton), and the kidneys (high blood calcium can lead to kidney stones). Many patients with mild PHPT also have low levels of vitamin D. Both PHPT and Vitamin D Deficiency weaken the skeleton. Recent medical guidelines recommend treating patients with PHPT and low Vitamin D levels with Vitamin D. Treatment with Vitamin D is particularly important in PHPT patients undergoing surgery to prevent postsurgical complications, such as a low blood calcium. This study is designed to determine how vitamin D should be replaced in patients with PHPT and low vitamin D. If you are interested in finding out more information, please contact our Study Coordinator.

Are you Eligible? (Inclusion Criteria)

Primary Hyperparathyroidism, Vitamin D Deficiency

Specialty Area(s)

Trial Location

United States