Physician’s Profile

Selim M. Arcasoy, MD

1
Top Doctor: 
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Affiliations: 
NewYork-Presbyterian/Columbia
NewYork-Presbyterian/Morgan Stanley Children's Hospital
Board Certificates: 
Internal Medicine
Critical Care Medicine
Expertise: 
Transplant Surgery
Pulmonary Disease Medicine
Pediatric Pulmonology
Respiratory Failure
Transplant Pulmonology
Lung Transplantation
Lung Transplant
Specialist in Lung Transplantation Surgery
Transplantation
Transplantation Surgery
Pediatric Transplant Surgery
Pediatric Pulmonology
Honors: 

2009 Inclusion in New York City Super Doctors, New York Times Magazine

2009 Inclusion in the ninth edition of America’s Top Doctors

2008 Inclusion in the eighth edition of America’s Top Doctors

2007 Inclusion in seventh edition of America’s Top Doctors and eleventh edition of Top Doctors: New York Metro Area

2006 Inclusion in sixth edition of America’s Top Doctors and tenth edition of Top Doctors: New York Metro Area

2005 Inclusion in fifth edition of America’s Top Doctors and ninth edition of Top Doctors: New York Metro Area

2004 Inclusion in fourth edition of America’s Top Doctors and eighth edition of Top Doctors: New York Metro Area

2003 Inclusion in third edition of America’s Top Doctors and seventh edition of Top Doctors: New York Metro Area

2002 Inclusion in second edition of America’s Top Doctors and sixth edition of Top Doctors: New York Metro Area

2002 Fellow of the American College of Physicians (F.A.C.P.)

2001 Fellow of the American College of Chest Physicians (F.C.C.P.)

1990 Rank Valedictorian of class in Ege University School of Medicine

Interests: 
Patient selection and outcomes on the waiting list for lung transplantation
Predictors and diagnosis of acute and chronic lung rejection
Novel immunosuppressive regimens and antimicrobial therapies in lung transplantation
Co-morbidities in advanced pulmonary disease
Lung volume reduction for emphysema
Idiopathic pulmonary fibrosis and pulmonary alveolar proteinosis
Pulmonary embolism and thrombolytic therapy
About: 

Dr. Arcasoy was recruited to Columbia University/NewYork-Presbyterian Hospital as the Medical Program Director of Lung Transplantation in 2001 from the University of Pennsylvania, where he was a key member of the Advanced Lung Disease and Lung Transplantation Program in the Division of Pulmonary and Critical Care Medicine. After his recruitment, he completely turned around the Lung Transplantation Program to rank amongst the top 5 to 10 programs in the country with regards to volume and top 1 to 3 programs in terms of patient survival. Under his leadership, the Lung Transplant Program has performed 60-70 transplants annually in the past 6 years with a record number of 71 transplants in 2017. Despite high transplant volumes and very sick pretransplant candidates, the survival of lung transplant recipients has remained significantly above the national average. Currently, 1-year survival of lung transplant recipients at Columbia University is 90%, 5-year survival 68%, and 10-year survival 46% (as compared to 85%, 55%, and 28% national average survival at the same time points).

Dr. Arcasoy has gained national and international reputation with various leadership roles in many professional organizations and scientific societies. He previously chaired the Thoracic Organ Transplant Committee of the American Society of Transplantation and the Transplant Network Steering Committee of the American College of Chest Physicians. Dr. Arcasoy is a Fellow of the American College of Physicians (FACP), American College of Chest Physicians (FCCP), and American Society of Transplantation (FAST). He serves as a reviewer for many scientific journals. Dr. Arcasoy has been named in America's Top Doctors and Top Doctors: New York Metro area in the past 16 consecutive years. He has also been selected in the New York Times Super Doctors list in the past 10 years.

Dr. Arcasoy's main research interests include outcomes of patients with advanced lung disease before and after lung transplantation, post-transplant complications, optimization of post-transplant immunosuppression via multicenter clinical trials and collaborative investigation in immune tolerance, studies of genetic testing for diagnosis of organ rejection, various post-transplant complications and lung allocation policy. His research has been published in journals such as the New England Journal of Medicine, American Journal of Respiratory and Critical Care Medicine, Annals of Internal Medicine, Chest, American Journal of Transplantation, Journal of Heart and Lung Transplantation, Gene Therapy, and Transplantation. Between 2011 and 2013, Dr. Arcasoy attended the Executive Program and obtained his Master of Public Health degree in Healthcare Policy and Management from Columbia University Mailman School of Public Health. He maintains a very busy clinical practice in addition to administration of the Lung Transplant Program, teaching and clinical research. He is also heavily engaged in philanthropy and works arm in arm with some of his grateful patients to raise funds to meet the needs of his Program and patients focusing on cutting-edge research, education and building a strong patient community.

Publications: 
Selected Publications (1997-2017): S.M. Arcasoy, J.D. Latoche, M. Gondor, R.A. Henderson, R. Hughey, O.J. Finn, J.M. Pilewski.  MUC1 and other sialoglycoconjugates inhibit adenovirus-mediated gene transfer to epithelial cells. Am J Respir Cell Mol Biol 1997;17:422-35. S.M. Arcasoy, J.D. Latoche, M. Gondor, B.R. Pitt, J.M. Pilewski.  Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro. Gene Therapy 1997;4:32-38. S.M. Arcasoy, J.D. Latoche, M. Gondor, R.A. Henderson, R. Hughey, O.J. Finn, J.M. Pilewski.  The effects of sialoglycoconjugates on adenovirus-mediated gene transfer to epithelial cells in vitro and in human airway xenografts. Chest 1997;111:142S-3S. S.M. Arcasoy, J.R. Jett.  Superior pulmonary sulcus tumors and the Pancoast’s syndrome. N Engl J Med 1997;337:1370-6. S.M. Arcasoy, J.W. Kreit.  Thrombolytic therapy of pulmonary embolism: a comprehensive review of current evidence. Chest 1999;115:1695-1707. S.M. Arcasoy, R.M. Kotloff.  Lung transplantation. N Engl J Med 1999;340:1081-91. S.M. Arcasoy, C. Hersh, J.D. Christie, D. Zisman, A. Pochettino, B.R. Rosengard, N.P. Blumenthal, H.I. Palevsky, J.E. Bavaria, R.M. Kotloff. Bronchogenic carcinoma Complicating Lung Transplantation. J Heart Lung Transplant 2001;20:1044-53. S.M. Arcasoy, J.D. Christie, A. Pochettino, B.R. Rosengard, N.P. Blumenthal, J.E. Bavaria, R.M. Kotloff. Characteristics and Outcomes of Patients with Sarcoidosis Listed for Lung Transplantation. Chest 2001;120:873-80. S.M. Arcasoy, J.D. Christie, V.A. Ferrari, M. St. John Sutton, D.A. Zisman, N.P. Blumenthal, A. Pochettino, R.M. Kotloff. Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease. Am J Respir Crit Care Med 2003;167:735-40. M.E. Bowdish, S.M. Arcasoy, J.S. Wilt, J.V. Conte, R.D. Davis, E.R. Garrity, M.L. Hertz, J.B. Orens, B.R. Rosengard, M.L. Barr. Surrogate markers and risk factors for lung allograft dysfunction. Am J Transplant 2004;4:1171-8. S.M. Kawut, A. Reyentovich, J.S. Wilt, R. Anzeck, D.J. Lederer, M.K. O’Shea, J.R. Sonett, S.M. Arcasoy. Outcomes of extended donor lung transplant recipients after lung transplantation. Transplantation 2005;79:310-6. S.M. Kawut, L. Shah, J.S. Wilt, E. Dwyer, P.A. Maani, T.H. Daly, M.K. O’Shea, J.R. Sonett, S.M. Arcasoy. Risk Factors and Outcomes of Hypogammaglobulinemia After Lung Transplantation. Transplantation 2005;79:1723-6. S.M. Arcasoy, A. Fisher, R.R. Hachem, M. Scavuzzo, L.B. Ware. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction. Part V: Predictors and Outcomes. J Heart Lung Transplant 2005;24:1483-8. N.H. Yip, D.J. Lederer, S.M. Kawut, J.S. Wilt, F. D'Ovidio, Y. Wang, E. Dwyer, J.R. Sonett, S.M. Arcasoy. Immunoglobulin G Levels Before and After Lung Transplantation. Am J Respir Crit Care Med 2006; 173:917-21. J.B. Orens, M. Estenne, S. Arcasoy, J.V. Conte, P. Corris, J.J. Egan, T. Egan, S. Keshvajee, C. Knoop, R. Kotloff, F.J. Martinez, S. Nathan, S. Palmer, A. Patterson, L. Singer, G. Snell, S. Studer, J.L. Vachiery, A.R. Glanville. International Guidelines for the Selection of Lung Transplant Candidates: 2006 Update. J Heart Lung Transplant 2006;25:745-55. A. Iribarne, M.J. Russo, R.R. Davies, K.N. Hong, A.C. Gelijns, M.D. Bacchetta, F. D'Ovidio, S. Arcasoy, J.R. Sonett. Despite Decreased Wait-List Times for Lung Transplantation, Lung Allocation Scores Continue to Increase. Chest 2009;135(4):923-8. M.R. Celik, D.J. Lederer, J. Wilt, D. Eser, M. Bacchetta, F. D'Ovidio, J.R. Sonett, S.M. Arcasoy. Tacrolimus and Azathioprine versus Cyclosporine and Mycophenolate Mofetil after Lung Transplantation: A Retrospective Cohort Study. J Heart Lung Transplant 2009;28:697-703. D.J. Lederer, J.S. Wilt, F. D'Ovidio, M.D. Bacchetta, L. Shah, S. Ravichandran, J. Lenoir, B. Klein, J.R. Sonett, S.M. Arcasoy. Obesity and Underweight are Associated with an Increased Risk of Death after Lung Transplantation. Am J Respir Crit Care Med 2009;180:887-95. M.J. Russo, R.R. Davies, K.N. Hong, A. Iribarne, S. Kawut, M. Bacchetta, F. D'Ovidio, S. Arcasoy, J.R. Sonett. Who is the high-risk recipient? Predicting mortality after lung transplantation using pretransplant risk factors. J Thorac Cardiovasc Surg 2009;138 1234-8. S.M. Arcasoy, G. Berry, C.C. Marboe, H.D. Tazelaar, M.R. Zamora, H.J. Wolters, K.C. Fang, S. Keshavjee for the LARGO Study Investigators. Pathologic Interpretation of Transbronchial Biopsy For Acute Rejection of Lung Allograft Is Highly Variable. Am J Transplant 2011;11:320-8. M.N. Bartels, H.F. Armstrong, R.E. Gerardo, A.M. Layton, B.O. Emmert-Aronson, J. Sonett, S. Arcasoy. Evaluation of Pulmonary Function and Exercise Performance by Cardiopulmonary Exercise Testing Before and After Lung Transplantation Chest 2011; 140:1604-11. J.L Hook, S.M. Arcasoy, D. Zemmel, M. Bartels, S.M. Kawut, D.J. Lederer. Titrated oxygen requirement and prognostication in idiopathic pulmonary fibrosis. Eur Respir J 2012;39:359-65. M.R. Baldwin, S.M. Arcasoy, A. Shah, P.C. Schulze, J. Sze, J.R. Sonett, D.J. Lederer.  Hypoalbuminemia and early mortality after lung transplantation: a cohort study.  Am J Transplant 2012;12:1256-67. J. Javidfar, D. Brodie, A. Iribarne, J. Jurado, M. LaVelle, K. Brenner, S. Arcasoy, J. Sonett, M. Bacchetta. Extracorporeal membrane oxygenation as a bridge to lung transplantation and recovery. J Thorac Cardiovasc Surg 2012;144:716-21. S.M. Bhorade, A.N. Husain, C. Liao, L. Chuan Li, V.N. Ahya, M.A. Baz, V.G.Valentine, R.B. Love, H.Seethamraju, C.G. Alex, R. Bag, N.C. DeOliveira, W.T. Vigneswaran, E.R. Garrity, S.M. Arcasoy.  Interobserver variability in grading transbronchial lung biopsies after lung transplantation. Chest 2013;143:1717-24. JL Sell, M Bacchetta, SB Goldfarb, H Park, PV Heffernan, HA Robbins, L Shah, K Raza, F D'Ovidio, JR Sonett, SM Arcasoy, DJ Lederer. Short Stature and Access to Lung Transplantation in the United States. A Cohort Study. Am J Respir Crit Care Med 2016;193(6):681-8. J. Costa, S. Sreekanth, A. Kossar, K. Raza, D.J. Lederer, H. Robbins, L. Shah, J.R. Sonett, S. Arcasoy, F. D'Ovidio. Donor lung assessment using selective pulmonary vein gases. Eur J Cardiothorac Surg 2016;50:826-31.  J. Costa, S. Sreekanth, A. Kossar, K. Raza, H. Robbins, L. Shah, J.R. Sonett, S. Arcasoy, F. D'Ovidio. Donors with a prior history of cardiac surgery are a viable source of lung allografts. Eur J Cardiothorac Surg 2016;50:822-25. A.M. Layton, H.F. Armstrong, H.P. Kim, K.S. Meza, F. D’Ovidio, S.M. Arcasoy. Cardiopulmonary exercise factors predict survival in patients with advanced interstitial lung disease referred for lung transplantation. Respir Med 2017; 126: 59-67 L.J. Benvenuto, D.R. Anderson, H.P. Kim, J.L. Hook, L. Shah, H.Y. Robbins, F. D’Ovidio, M. Bacchetta, J.R. Sonett, S.M. Arcasoy. Geographic disparities in donor lung supply and lung transplant waitlist outcomes: A Cohort Study. Am J Transplant; 2017: DOI: 10.1111/ajt.14630. Arcasoy SM.Selection of patients with cystic fibrosis for lung transplantation.In: Braunwald E,Fauci AS,Isselbacher KJ,Kasper DL,Hauser SL,Longo DL,Jameson JL (Eds.) HarrisonsOnline.2007. Lederer DJ,Caplan-Shaw CE,O'Shea MK,Wilt JS,Basner RC,Bartels MN,Sonett JR,Arcasoy SM,Kawut SM.Racial and ethnic disparities in survival in lung transplant candidates with idiopathic pulmonary fibrosis.Am J Transplant 2006;6(2):398-403. Lederer DJ,Arcasoy SM,Wilt JS,D'Ovidio F,Sonett JR,Kawut SM.Six-minute Walk Distance Predicts Waiting List Survival in Idiopathic Pulmonary Fibrosis.Am J Respir Crit Care Med 2006;174:659-64. Lederer DJ,Arcasoy SM,Barr RG,Wilt JS,Bagiella E,D'Ovidio F,Sonett JR,Kawut SM.Racial and Ethnic Disparities in Idiopathic Pulmonary Fibrosis: A UNOS/OPTN Database Analysis.Am J Transplant 2006;6:2436-42. Caplan-Shaw CE,Arcasoy SM,Shane E,Lederer DJ,Wilt JS,O'Shea MK,Addesso V,Sonett JR,Kawut SM.Osteoporosis in diffuse parenchymal lung disease.Chest 2006 Jan;129(1):140-6.Erratum in: Chest 2006 Mar;129(3):831. Yip NH,Lederer DJ,Kawut SM,Wilt JS,D'Ovidio F,Wang Y,Dwyer E,Sonett JR,Arcasoy SM.Immunoglobulin G levels before and after lung transplantation.Am J Respir Crit Care Med 2006 Apr 15;173(8):917-21. Arcasoy SM,Wilt J.Medical complications after lung transplantation.Sem Respir Crit Care Med 2006;27:508-20. Orens JB,Estenne M,Arcasoy SM,Conte JV,Corris P,Egan JJ,Egan T,Keshvajee S,Knoop C,Kotloff R,Martinez FJ,Nathan S,Palmer S,Patterson A,Singer L,Snell G,Studer S,Vachiery JL,Glanville AR.International Guidelines for the Selection of Lung Transplant Candidates: 2006 Update.J Heart Lung Transplant 2006;25:745-55. Lederer DJ,Kawut SM,Sonett JR,Vakiani E,Seward SL Jr,White JG,Wilt JS,Marboe CC,Gahl WA,Arcasoy SM.Successful bilateral lung transplantation for pulmonary fibrosis associated with the Hermansky-Pudlak syndrome.J Heart Lung Transplant 2005 Oct;24(10):1697-9. Arcasoy SM,Fisher A,Hachem RR,Scavuzzo M,Ware LB; ISHLT Working Group on Primary Lung Graft Dysfunction.Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part V: predictors and outcomes.J Heart Lung Transplant 2005 Oct;24(10):1483-8. Kawut SM,Shah L,Wilt JS,Dwyer E,Maani PA,Daly TM,O'Shea MK,Sonett JR,Arcasoy SM.Risk factors and outcomes of hypogammaglobulinemia after lung transplantation.Trans