Researcher’s Profile

Erika Berman Rosenzweig, MD

Director, Pulmonary Hypertension Comprehensive Care Center at Columbia University Medical Center/NewYork-Presbyterian Hospital
Associate Chief, Division of Pediatric Cardiology
Director, CTEPH-PTE Program at CUMC - NYP
Overview: 

Dr. Berman Rosenzweig has extensive experience performing clinical research trials in the field of pulmonary vascular disease, which have been mostly focused on the study of novel medical treatments for pulmonary arterial hypertension and the genomics of pulmonary hypertension.  She has spent the past 16 years collaborating on novel drug trials to improve the options available for patients with pulmonary hypertension and has participated in most of the pivotal clinical trials which prompted FDA approval for these agents. She has also collaborated with genetics teams at CUMC and abroad, who have discovered genetic mutations associated with PAH, and was recently one of six US centers awarded a UO1 grant from NHLBI for the study of PVDOMICS, a collaborative study aimed at defining the future fingerprints of pulmonary vascular disease.

Despite the major advances in medical treatment of PH, there is still no medical cure, and patients often die waiting for lung transplantation given the shortage of suitable donor organs. In response to this need, Dr. Berman Rosenzweig has applied her clinical expertise toward research focused on novel approaches to artificial heart-lung support for pulmonary hypertension.

Publications: 
Zhu N, Welch CL, Wang J, Allen PM, Gonzaga-Jauregui C, Ma L, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Pauciulo MW, Lutz KA, Nichols WC, Reid JG, Overton JD, Baras A, Dewey FE, Shen Y, Chung WK. Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease. Genome Med. 2018 Jul 20;10(1):56. PMID: 30029678.
Zhu N, Gonzaga-Jauregui C, Welsh CL, Ma L, Qi H, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Nichols WC, Pauciulo MW, Lutz KA, Sawle A, Reid JG, Overton JD, Baras A, Dewey F, Shen Y, Chung WK. Exome Sequencing in Children with Pulmonary Arterial Hypertension demonstrates differences compared with Adults. Circ Genom Prec Med. 2018.
Chicotka S, Pedroso FE, Agerstrand CL, Rosenzweig EB, Abrams D, Benson T, Layton A, Burkoff D, Brodie D, Bacchetta MD. Increased Opportunity for Lung Transplantation in Interstitial Lung Disease with Pulmonary Hypertension. Ann Thorac Surg 2018.
Position Paper for the Organization of ECMO for cardiac failure in adults. 2018Abrams D, Garan AR, Abdelbary A, Bacchetta M, Bartlett RH, Beck J, Belohlavek J, Chen YS, Fan E, Ferguson ND, Fowles JA, Fraser J, Gong M, Hassan IF, Hodgson C, Hou X, Hryniewicz K, Ichiba S, Jakobleff WA, Lorusso R, MacLaren G, McGuinness S, Mueller T, Park PK, Peek G, Pellegrino V, Price S, Rosenzweig EB, Sakamoto T, Salazar L, Schmidt M, Slutsky AS, Spaulding C, Takayama H, Takeda K, Vuylsteke A, Combes A, Brodie D; International ECMO Network (ECMONet) and The Extracorporeal Life Support Organization (ELSO). Intensive Care Med. 2018 Feb 15.
Elinoff JM, Agarwal R, Barnett CF,Benza RL, Cuttica MJ, Gharib AM, Gray MP, Hassoun, PM, Hemnes AR, Humbert M, Kolb TM, Lahm T, Leopold JA, Mathai SC, McLaughlin VV, Preston IR, Rosenzweig EB, Sholbin OA, Steen VD, Zamanian RT, Solomon MA.Challenges in Pulmonary Hypertension: Controversies in Treating the Tip of the Iceberg. Am J Resp Crit Care Med. 2018.
About: 

Dr. Erika Berman Rosenzweig, Director of the Pulmonary Hypertension Center at Columbia University Medical Center/NewYork-Presbyterian Hospital and the CTEPH Program at CUMC, is considered an international expert in the field of pulmonary hypertension. She has tremendous clinical and research experience in the fields of adult and pediatric pulmonary hypertension. Dr. Rosenzweig is widely published and has devoted remarkable efforts toward clinical research on the study of novel treatments and genetic causes of pulmonary hypertension as well as novel approaches to mechanical support for patients with end-stage pulmonary hypertension. She has been an active member of the Pulmonary Hypertension Association (PHA) and is currently on the Board of Trustees of the PHA, Immediate past Chair of the Scientific Leadership Council of the PHA, past Chair of the Review Committee for PHCC PH Center Accreditation Program, and past Editor-in Chief of the medical journal Advances in Pulmonary Hypertension.