Researcher’s Profile

Maryjane Anna Farr, MD

Medical Director, Adult Heart Transplant Program
Publications: 
1: See SB, Clerkin KJ, Kennel PJ, Zhang F, Weber MP, Rogers KJ, Chatterjee D, Vasilescu ER, Vlad G, Naka Y, Restaino SW, Farr MA, Topkara VK, Colombo PC, Mancini DM, Schulze PC, Levin B, Zorn E. Ventricular assist device elicits serum natural IgG that correlates with the development of primary graft dysfunction following heart transplantation. J Heart Lung Transplant. 2017 Mar 24. pii: S1053-2498(17)31733-3. doi: 10.1016/j.healun.2017.03.018. [Epub ahead of print] PubMed PMID: 28431981. 2: Davies RR, Farr M, Silvestry S, Callahan LR, Edwards L, Meyer DM, Uccellini K, Chan KM, Rogers JG. The new United States heart allocation policy: Progress through collaborative revision. J Heart Lung Transplant. 2017 Mar 21. pii: S1053-2498(17)31707-2. doi: 10.1016/j.healun.2017.03.010. [Epub ahead of print] PubMed PMID: 28396089. 3: Takeda K, Li B, Garan AR, Topkara VK, Han J, Colombo PC, Farr MA, Naka Y, Takayama H. Improved outcomes from extracorporeal membrane oxygenation versus ventricular assist device temporary support of primary graft dysfunction in heart transplant. J Heart Lung Transplant. 2016 Dec 23. pii: S1053-2498(16)30466-1. doi: 10.1016/j.healun.2016.12.006. [Epub ahead of print] PubMed PMID: 28087104. 4: Clerkin KJ, Farr MA, Restaino SW, Zorn E, Latif F, Vasilescu ER, Marboe CC, Colombo PC, Mancini DM. Donor-specific anti-HLA antibodies with antibody-mediated rejection and long-term outcomes following heart transplantation. J Heart Lung Transplant. 2017 May;36(5):540-545. doi: 10.1016/j.healun.2016.10.016. Epub 2016 Nov 17. PubMed PMID: 27916323. 5: Clerkin KJ, Farr MA, Restaino SW, Ali ZA, Mancini DM. Dobutamine stress echocardiography is inadequate to detect early cardiac allograft vasculopathy. J Heart Lung Transplant. 2016 Aug;35(8):1040-1. doi: 10.1016/j.healun.2016.05.012. Epub 2016 May 21. PubMed PMID: 27318788. 6: Varr BC, Restaino SW, Farr M, Scully B, Colombo PC, Naka Y, Mancini DM. Infectious complications after cardiac transplantation in patients bridged with mechanical circulatory support devices versus medical therapy. J Heart Lung Transplant. 2016 Sep;35(9):1116-23. doi: 10.1016/j.healun.2016.04.016. Epub 2016 May 11. PubMed PMID: 27289301. 7: Lee M, Akashi H, Kato TS, Takayama H, Wu C, Xu K, Collado E, Weber MP, Kennel PJ, Brunjes DL, Ji R, Naka Y, George I, Mancini D, Farr M, Schulze PC. Vascular inflammation and abnormal aortic histomorphometry in patients after pulsatile- and continuous-flow left ventricular assist device placement. J Heart Lung Transplant. 2016 Sep;35(9):1085-91. doi: 10.1016/j.healun.2015.12.027. Epub 2016 Jan 6. PubMed PMID: 26899764; PubMed Central PMCID: PMC5376500. 8: Lewis M, Ginns J, Schulze C, Lippel M, Chai P, Bacha E, Mancini D, Rosenbaum M, Farr M. Outcomes of Adult Patients With Congenital Heart Disease After Heart Transplantation: Impact of Disease Type, Previous Thoracic Surgeries, and Bystander Organ Dysfunction. J Card Fail. 2016 Jul;22(7):578-82. doi: 10.1016/j.cardfail.2015.09.002. Epub 2015 Nov 11. PubMed PMID: 26432646. 9: Kato TS, Armstrong HF, Schulze PC, Lippel M, Amano A, Farr M, Bacchetta M, Bartels MN, Di Tullio MR, Homma S, Mancini D. Left and Right Ventricular Functional Dynamics Determined by Echocardiograms Before and After Lung Transplantation. Am J Cardiol. 2015 Aug 15;116(4):652-9. doi: 10.1016/j.amjcard.2015.05.027. Epub 2015 May 21. PubMed PMID: 26089014; PubMed Central PMCID: PMC4522196. 10: Farr M, Mitchell J, Lippel M, Kato TS, Jin Z, Ippolito P, Dove L, Jorde UP, Takayama H, Emond J, Naka Y, Mancini D, Lefkowitch JH, Schulze PC. Combination of liver biopsy with MELD-XI scores for post-transplant outcome prediction in patients with advanced heart failure and suspected liver dysfunction. J Heart Lung Transplant. 2015 Jul;34(7):873-82. doi: 10.1016/j.healun.2014.12.009. Epub 2014 Dec 23. PubMed PMID: 25851466; PubMed Central PMCID: PMC4941637. 11: Farr M, Schulze PC. Recent advances in the diagnosis and management of cirrhosis-associated cardiomyopathy in liver transplant candidates: advanced echo imaging, cardiac biomarkers, and advanced heart failure therapies. Clin Med Insights Cardiol. 2015 Jan 28;8(Suppl 1):67-74. doi: 10.4137/CMC.S15722. eCollection 2014. Review. PubMed PMID: 25657603; PubMed Central PMCID: PMC4310615. 12: Martin ST, Kato TS, Farr M, McKeen JT, Cheema F, Ji M, Ross A, Yerebakan H, Naka Y, Takayama H, Restaino S, Mancini D, Schulze PC. Similar survival in patients following heart transplantation receiving induction therapy using daclizumab vs. basiliximab. Circ J. 2015;79(2):368-74. doi: 10.1253/circj.CJ-14-0718. Epub 2014 Dec 12. PubMed PMID: 25501951; PubMed Central PMCID: PMC4967552. 13: Clerkin KJ, Thomas SS, Haythe J, Schulze PC, Farr M, Takayama H, Jorde UP, Restaino SW, Naka Y, Mancini DM. Mechanical circulatory support as a bridge to cardiac retransplantation: a single center experience. J Heart Lung Transplant. 2015 Feb;34(2):161-6. doi: 10.1016/j.healun.2014.09.033. Epub 2014 Sep 28. PubMed PMID: 25455751; PubMed Central PMCID: PMC4936397. 14: Pronschinske KB, Qiu S, Wu C, Kato TS, Khawaja T, Takayama H, Naka Y, Templeton DL, George I, Farr MA, Mancini DM, Schulze PC. Neutrophil gelatinase-associated lipocalin and cystatin C for the prediction of clinical events in patients with advanced heart failure and after ventricular assist device placement. J Heart Lung Transplant. 2014 Dec;33(12):1215-22. doi: 10.1016/j.healun.2014.06.007. Epub 2014 Jun 23. PubMed PMID: 25049066; PubMed Central PMCID: PMC4252882. 15: Kato TS, Jiang J, Schulze PC, Jorde U, Uriel N, Kitada S, Takayama H, Naka Y, Mancini D, Gillam L, Homma S, Farr M. Serial echocardiography using tissue Doppler and speckle tracking imaging to monitor right ventricular failure before and after left ventricular assist device surgery. JACC Heart Fail. 2013 Jun;1(3):216-22. doi: 10.1016/j.jchf.2013.02.005. Epub 2013 Jun 3. PubMed PMID: 24621873; PubMed Central PMCID: PMC3997790. 16: Sera F, Kato TS, Farr M, Russo C, Jin Z, Marboe CC, Di Tullio MR, Mancini D, Homma S. Left ventricular longitudinal strain by speckle-tracking echocardiography is associated with treatment-requiring cardiac allograft rejection. J Card Fail. 2014 May;20(5):359-64. doi: 10.1016/j.cardfail.2014.02.006. Epub 2014 Feb 21. PubMed PMID: 24561182. 17: Kato TS, Kitada S, Yang J, Wu C, Takayama H, Naka Y, Farr M, Mancini DM, Schulze PC. Relation of preoperative serum albumin levels to survival in patients undergoing left ventricular assist device implantation. Am J Cardiol. 2013 Nov 1;112(9):1484-8. doi: 10.1016/j.amjcard.2013.06.023. Epub 2013 Jul 25. PubMed PMID: 23891248; PubMed Central PMCID: PMC4074378. 18: Kitada S, Kato TS, Thomas SS, Conwell SD, Russo C, Di Tullio MR, Farr M, Schulze PC, Uriel N, Jorde UP, Takayama H, Naka Y, Homma S, Mancini DM. Pre-operative echocardiographic features associated with persistent mitral regurgitation after left ventricular assist device implantation. J Heart Lung Transplant. 2013 Sep;32(9):897-904. doi: 10.1016/j.healun.2013.06.004. Epub 2013 Jul 11. PubMed PMID: 23850122; PubMed Central PMCID: PMC4278424. 19: Kato TS, Collado E, Khawaja T, Kawano Y, Kim M, Farr M, Mancini DM, Schulze PC. Response to letter regarding article, "Value of peak exercise oxygen consumption combined with B-type natriuretic peptide levels for optimal timing of cardiac transplantation". Circ Heart Fail. 2013 May;6(3):e42. PubMed PMID: 23844429; PubMed Central PMCID: PMC4959007. 20: Kato TS, Cheema FH, Yang J, Kawano Y, Takayama H, Naka Y, Farr M, Lederer DJ, Baldwin MR, Jin Z, Homma S, Mancini DM, Schulze PC. Preoperative serum albumin levels predict 1-year postoperative survival of patients undergoing heart transplantation. Circ Heart Fail. 2013 Jul;6(4):785-91. doi: 10.1161/CIRCHEARTFAILURE.111.000358. Epub 2013 May 14. PubMed PMID: 23674361; PubMed Central PMCID: PMC4074373. 21: Kim MS, Kato TS, Farr M, Wu C, Givens RC, Collado E, Mancini DM, Schulze PC. Hepatic dysfunction in ambulatory patients with heart failure: application of the MELD scoring system for outcome prediction. J Am Coll Cardiol. 2013 Jun 4;61(22):2253-61. doi: 10.1016/j.jacc.2012.12.056. Epub 2013 Apr 3. PubMed PMID: 23563127; PubMed Central PMCID: PMC3939720. 22: Schulze PC, Jiang J, Yang J, Cheema FH, Schaeffle K, Kato TS, Farr M, Restaino S, Deng M, Maurer M, Horn E, Latif F, Colombo PC, Jorde U, Uriel N, Haythe J, Bijou R, Drusin R, Lee SH, Takayama H, Naka Y, Mancini DM. Preoperative assessment of high-risk candidates to predict survival after heart transplantation. Circ Heart Fail. 2013 May;6(3):527-34. doi: 10.1161/CIRCHEARTFAILURE.112.000092. Epub 2013 Mar 15. PubMed PMID: 23505300; PubMed Central PMCID: PMC4283202. 23: Penn MS, Mendelsohn FO, Schaer GL, Sherman W, Farr M, Pastore J, Rouy D, Clemens R, Aras R, Losordo DW. An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure. Circ Res. 2013 Mar 1;112(5):816-25. doi: 10.1161/CIRCRESAHA.111.300440. Epub 2013 Feb 21. PubMed PMID: 23429605. 24: Kato TS, Stevens GR, Jiang J, Schulze PC, Gukasyan N, Lippel M, Levin A, Homma S, Mancini D, Farr M. Risk stratification of ambulatory patients with advanced heart failure undergoing evaluation for heart transplantation. J Heart Lung Transplant. 2013 Mar;32(3):333-40. doi: 10.1016/j.healun.2012.11.026. PubMed PMID: 23415315; PubMed Central PMCID: PMC4119928. 25: Kato TS, Collado E, Khawaja T, Kawano Y, Kim M, Farr M, Mancini DM, Schulze PC. Value of peak exercise oxygen consumption combined with B-type natriuretic peptide levels for optimal timing of cardiac transplantation. Circ Heart Fail. 2013 Jan;6(1):6-14. doi: 10.1161/CIRCHEARTFAILURE.112.968123. Epub 2012 Nov 30.
About: 

Maryjane Farr, MD, MSc, FACC is an Associate Professor of Medicine at Columbia University Medical Center/New York-Presbyterian Hospital. Dr. Farr received her Doctorate in Medicine from Columbia University College of Physicians and Surgeons, AOA and Master's in Science at Columbia University Mailman School of Public Health.

Dr. Farr completed her internal medicine internship and residency at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. Dr. Farr went on to complete an ACGME cardiovascular diseases fellowship at Weill Cornell Medical College. She completed advanced heart failure and transplantation fellowship training at Columbia University Medical Center, Montefiore Medical Center and The Brigham and Women's Hospital. Dr. Farr is board certified in Internal Medicine, Cardiovascular Diseases, Echocardiography and Heart Failure and Transplantation.

In 2009 Dr. Farr became a Patient-Oriented Research Scholar through an NIH training grant, completing a Master's in Science in 2011. In 2012 Dr. Farr was honored as a Heart Failure and Transplant Scholar, with the Shorin-Silverstein Grant from Columbia University Medical Center.

Dr. Farr has been a member of the UNOS Thoracic Committee since 2015, as Region 9 Representative and currently as the Heart Subcommittee Chair. She is on the Medical Advisory Board of LiveOn NY and a member fo the NY Cardiothoracic Transplant Consortium. Dr. Farr has been the Medical Director of Adult Heart Transplantation at NYP/Columbia since 2014.