Pancreatic Cancer Diagnosis, Prevention, and Treatment
Depression is classified in the DSM-IV as persistent depressed mood most of the time for a period of two weeks, appetite and sleep disturbances, and decreased energy and attention.
In one large clinical study only 17% of patients, who had an average of approximately 28 days of life left, had clinical depression (Breitbart & Heller, 2003).
Observations have been made that the prevalence of psychiatric symptoms appears high in the pancreatic cancer patient population. The review by Green and Austin (1993) suggests that the psycho-pathology of pancreatic tumors may also be linked to tumor induced changes in neuroendocrine or acid base systems, although confirmatory data are lacking (Fitzsimmons et al, 1999).