Physician’s Profile

Paolo C. Colombo, MD

Assistant Attending Physician, Center for Advanced Cardiac Care
Assistant Attending Physician, Coronary Care Unit
Medical Director Mechanical of the Circulatory Support Program
Director, Center for Advanced Cardiac Care
Board Certificates: 
Advanced Heart Failure and Transplant Cardiology
Cardiovascular Disease
Left Ventricular Assist Devices (LVAD)
Heart Transplant Management
Congestive Heart Failure (CHF)
Mechanical Assist Device
Heart Failure

Paolo C. Colombo is a cardiologist who specialized in treating patients with heart failure, cardiac assist device and heart transplant. Dr. Colombo is board certified in Cardiovascular Disease and in Advanced Heart Failure and Transplant Cardiology.

Dr. Colombo received his medical degree, magna cum laude from the University of Milan in Italy. He completed his internal medicine residency and fellowship at Montefiore Medical Center, the university hospital for the Albert Einstein College of Medicine in New York. He then specialized in heart failure and transplant at NewYork-Presbyterian Hospital/Columbia University Medical Center in New York.

Dr. Colombo has been on ColumbiaDoctors faculty since 2002. He is the Sudhir Choudhrie Professor of Cardiology and serves as the Director of the Center for Advanced Cardiac: Heart Failure, Heart Transplant and Mechanical Circulatory Support.

An internationally renowned investigator, Dr. Colombo has been awarded research grants from the National Institutes of Health, American Heart Association as well as other research foundations. Dr. Colombo has published more than 160 manuscripts and presented his research all over the world.

Dr. Colombo sees patients at Columbia University Medical Center in Washington Heights.

Colombo PC, Ashton AW, Celaj S, Talreja A, Banchs JE, DuBois NB, Marinaccio M, Malla S, Lachmann J, Ware JA, Le Jemtel TH. Biopsy Coupled to Quantitative Immunofluorescence: a New Method to Study the Human Vascular Endothelium. J Appl Physiol 92:1331-8, 2002
Colombo PC, Banchs JE, Lachmann J, Malla S, Celaj S, Nicholas B. DuBois NB, Talreja A, Ashton AW, Jorde UP, Ware JA, Le Jemtel TH. Vascular Endothelial Cell Activation in Patients With Decompensated Heart Failure. Response to Short-Term Inotropic Therapy. Circulation 111:58-62, 2005
Onat D, Jelic J, Schmidt AM , Pile-Spellman J, Homma S, Padeletti M, Jin Z, Le Jemtel TH,  Colombo PC* & Feng L* (*Senior Authors). Vascular Endothelial Sampling and Analysis of Gene Transcripts: a New Quantitative Approach to Monitor Vascular Inflammation. J Applied Physiol 103:1873-8, 2007
Vittorio T,   Zolty R, Parveen K, Garg PK, Sarswat N, Tseng CH, , Jorde UP, Colombo PC.  Interdependence of Cardiac and Endothelial Function in Patients with Chronic Heart Failure on Optimal Medical Therapy. Echocardiography 26:916-21,2009
Dini FL, Demmer RT, Simionuc A , Donati F, Dell’Anna R, Orsini E, Caravelli P, Marzilli M, Colombo PC. Right Ventricular Function Predicts Chronic Kidney Disease and Survival in Patients With Chronic Systolic Heart Failure. Eur J Heart Fail 14:287-94, 2012
Uriel N, Morrison KA, Garan AR, Kato TS, Yuzefpolskaya M, Latif F, Restaino SW, Mancini DM, Flannery M, Takayama H, John R, Colombo PC, Naka Y, Jorde UP. Development of a Novel Echocardiography Ramp Test for Speed Optimization and Diagnosis of Device Thrombosis in Continuous-Flow Left Ventricular Assist Devices: The Columbia Ramp Study. J Am Coll Cardiol 60:1764-75,  2012
Garan AR, Yuzefpolskaya M, Colombo PC, Morrow JP, Te-Frey R, Dano D, Takayama H, Naka Y, Garan H, Jorde UP, Uriel N. Ventricular Arrhythmias and ICD therapy in Patients with Continuous Flow Left Ventricular Assist Devices: Need for Primary Prevention? J Am Coll Cardiol. 61:2542-50, 2013.
Lanier G, Orlanes K, Hayashi Y, Murphy J, Flannery M, Te-Frey R, Uriel U, Yuzefpolskaya M,  Mancini DM, Naka Y, Takayama H, Jorde UP, Demmer RT, Colombo PC. Validity and Reliability of a Novel Slow Cuff-Deflation System for Non-Invasive Blood Pressure Monitoring in Patients with Continuous-Flow Left Ventricular Assist Device. Circ Heart Fail 6:1005-12, 2013.
Ota T, Yerebakan H, Akashi H, Takayama H, Uriel N, Colombo PC, Jorde UP, Naka Y. Continuous-flow left ventricular assist device exchange: Clinical outcomes. J Heart Lung Transplant. S1053-2498:01343-0, 2013.
Uriel N, Han J, Morrison KA, Nahumi N, Yuzefpolskaya M, Garan AR, Duong J, Colombo PC, Takayama H, Thomas S, Naka Y, Jorde UP. Device thrombosis in HeartMate II continuous-flow left ventricular assist devices: A multifactorial phenomenon.. J Heart Lung Transplant. 33:51-9, 2014. 
Colombo PC, Onat D, Harxhi A, Demmer RT, Hayashi Y,  Jelic S, LeJemtel TH, Bucciarelli L, Kebschull M, Papapanou P, Uriel N, Schmidt AM, Sabbah HN, Jorde UP. Peripheral Venous Congestion Causes Inflammation, Neurohormonal and Endothelial Cell Activation. Eur Heart J. 35:448-54, 2014.
Colombo PC, Doran AC, Onat D, Wong KY, Ahmad M, Sabbah HN, Demmer RT. Venous Congestion, Endothelial and Neurohormonal Activation in Acute Decompensated Heart Failure: Cause or Effect?  Curr Heart Fail Rep. 12(3):215-22, 201
Yuzefpolskaya M, Uriel N, Flannery M, Yip N, Mody K, Cagliostro B, Takayama H, Naka Y, Jorde UP, Goswami S, Colombo PC. Advanced cardiovascular life support algorithm for the management of the hospitalized unresponsive patient on continuous flow left ventricular assist device support outside the intensive care unit. Eur Heart J Acute Cardiovasc Care. [Epub ahead of print] 2015.
Mancini DM, Colombo PC. Left Ventricular Assist Devices: A Rapidly Evolving Alternative to Transplant. J Am Coll Cardiol. 65:2542-2555, 2015.
Colombo PC, Lanier GM, Orlanes K, Yuzefpolskaya M, Demmer RT. Usefulness of a standard automated blood pressure monitor in patients with continuous-flow left ventricular assist devices.  J Heart Lung Transplant. S1053-2498, 2015.
Willey JZ, Boehme AK, Castagna F, Yuzefpolskaya M, Garan AR, Topkara V, Colombo PC. Hypertension and Stroke in Patients with Left Ventricular Assist Devices (LVADs). Curr Hypertens Rep. 18:12, 2016.
Willey JZ,  Gavalas MV, Yuzefpolskaya M, Garan AR, Levin AP, Takeda K, MD, PhD3; Takayama H, Fried J, Naka Y, Topkara VK, Colombo PC.  Outcomes after stroke complicating left ventricular assist device. J Heart Lung Transplant.  35: 1003-9, 2016.
Myocardial Recovery in Patients Receiving Contemporary Left Ventricular Assist Devices: Results From the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS). Topkara VK, Garan AR, Fine B, Godier-Furnémont AF, Breskin A, Cagliostro B, Yuzefpolskaya M, Takeda K, Takayama H, Mancini DM, Naka Y, Colombo PC. Circ Heart Fail. 9(7), 2016.
Gavalas MV, Breskin A, Yuzefpolskaya M, Eisenberger A, Castagna F, Demmer RT, Flannery M, Garan AR, Takeda K, Takayama H, Naka Y, Topkara VK, Colombo PC. Discriminatory performance of positive urine hemoglobin for detection of significant hemolysis in patients with continuous-flow left ventricular assist devices. J Heart Lung Transplant. 2016 [Epub ahead of print]