Congenital heart anomalies are the most common birth defects in the United States. Each year, approximately 10,000 babies (1 of every 115), born in the U.S. have a congenital heart defect that will require operative repair with the aid of cardiopulmonary bypass (CPB) during early childhood. Approximately 26,000 children (aged 0 to 5 years) annually will undergo procedures that require CPB.
Although complex surgical corrections now entail lower mortality rates than ever before, injury to vital organ (the brain, kidneys, lungs and heart) after normothermic/hypothermic CPB, with or without deep hypothermic circulatory arrest (DHCA), occurs in significant number of postoperative pediatric heart patients. Vital organ injury affects the short and long term outcomes in this group. Pediatric cardiac patients, particularly neonates and infants, are more susceptible to the inflammatory response, capillary leak syndrome and multi-organ dysfunction due to immature organ systems with altered homeostasis, reactive pulmonary vasculature and higher metabolic demands.
Pediatrics cardiac surgeons, cardiologists, intensivists, scientists, engineers, perfusionists, nurses, respiratory therapists, anesthesiologists, pediatric fellows, residents & engineering and medical students.
- Evaluate the impact of unique features and outcomes for pediatric mechanical circulatory support systems.
- Compare the benefits and risks of current and new extracorporeal life support systems (ECLS) systems.
- Determine how and where to implement cutting edge bioengineering approaches in their practice of pediatric cardiovascular medicine.
Columbia University Medical Center
Department of Surgery, Office of External Affairs
400 Kelby Street, Floor 11, Fort Lee, NJ 07024