Bunnett Lab

Nigel W. Bunnett, B.Sc, PhDPI: Nigel W. Bunnett, B.Sc, PhD

Location

P&S Building – 630 W 168th Street, 10-401
New York, NY 10032

Research

Dr. Bunnett’s research focuses on two families of proteins at the surface of nerve cells that control pain, itch and inflammation: G protein-coupled receptors and transient receptor potential ion channels. G protein-coupled receptors are the largest class of signaling proteins, participate in all physiological and patho-physiological processes, and are the target of one third of clinically used drugs. The small family of transient receptor potential ion channels also control important biological processes and are an emerging therapeutic target. G protein-coupled receptors and transient receptor potential ion channels allow nerves to sense noxious, irritating and inflammatory stimuli. Their activation leads to the sensations of pain and itch, and controls the process of inflammation.

Lab Members

  • Rocco Latorre, PhD – Postdoctoral Research Scientist
  • Rafael Klein-Cloud, MD – Pediatric ECMO Fellow
  • Alan Hegron, PhD – Postdoctoral Research Scientist
  • Jeong Lee – Technician
  • Matthew Wisdom – Student Intern
  • Daeun Bok – Barnard Undergraduate Student

Lab Collaborators

  • Alex Thomsen, PhD – Assistant Professor
  • Dane Jensen, PhD – Assistant Professor