Researcher’s Profile

Erika S Berman Rosenzweig, MD

Associate Chief, Division of Pediatric Cardiology
Director, Pulmonary Hypertension Comprehensive Care Center at Columbia University Medical Center/NewYork-Presbyterian Hospital
Director, CTEPH Program at CUMC - NYP
Overview: 

Dr. Berman Rosenzweig has extensive experience performing clinical research trials in the field of pulmonary vascular disease, which have been mostly focused on the study of novel medical treatments for pulmonary arterial hypertension and the genomics of pulmonary hypertension. She has spent the past 16 years collaborating on novel drug trials to improve the options available for patients with pulmonary hypertension and has participated in most of the pivotal clinical trials which prompted FDA approval for these agents. She has also collaborated with genetics teams at CUMC and abroad, who have discovered genetic mutations associated with PAH, and was recently one of six US centers awarded a UO1 grant from NHLBI for the study of PVDOMICS, a collaborative study aimed at defining the future fingerprints of pulmonary vascular disease.

Despite the major advances in medical treatment of PH, there is still no medical cure, and patients often die waiting for lung transplantation given the shortage of suitable donor organs. In response to this need, Dr. Berman Rosenzweig has applied her clinical expertise toward research focused on novel approaches to artificial heart-lung support for pulmonary hypertension.

Publications: 
Rosenzweig EB, Ankola A, Krishnan U, Middlesworth W, Bacha E, Bacchetta M. A novel unidirectional-valved shunt approach for end-stage pulmonary arterial hypertension: Early experience in adolescents and adults. J Thorac Cardiovasc Surg. 2019 Nov 14.
Rosenzweig EB, Gannon WD, Madahar P, Agerstrand C, Abrams D, Liou P, Brodie D, and Bacchetta M. Extracorporeal life support bridge for pulmonary hypertension: A high-volume single-center experience. JHLT, Published online: September 12, 2019, JHLT.
Rosenzweig EB, Abman SH, Adatia I, Beghetti M, Bonnet D, Haworth S, Ivy DD, Berger RMF. Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management. Eur Respir J. 2019 Jan 24;53(1).
Zhu N, Welch CL, Wang J, Allen PM, Gonzaga-Jauregui C, Ma L, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Pauciulo MW, Lutz KA, Nichols WC, Reid JG, Overton JD, Baras A, Dewey FE, Shen Y, Chung WK. Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease. Genome Med. 2018 Jul 20;10(1):56. PMID: 30029678.
Zhu N, Gonzaga-Jauregui C, Welsh CL, Ma L, Qi H, King AK, Krishnan U, Rosenzweig EB, Ivy DD, Austin ED, Hamid R, Nichols WC, Pauciulo MW, Lutz KA, Sawle A, Reid JG, Overton JD, Baras A, Dewey F, Shen Y, Chung WK. Exome Sequencing in Children with Pulmonary Arterial Hypertension demonstrates differences compared with Adults. Circ Genom Prec Med. 2018.
About: 

Dr. Erika Berman Rosenzweig, Director of the Pulmonary Hypertension Center at Columbia University Medical Center/NewYork-Presbyterian Hospital and the CTEPH Program at CUMC, is considered an international expert in the field of pulmonary hypertension. She has tremendous clinical and research experience in the fields of adult and pediatric pulmonary hypertension. Dr. Rosenzweig is widely published and has devoted remarkable efforts toward clinical research on the study of novel treatments and genetic causes of pulmonary hypertension as well as novel approaches to mechanical support for patients with end-stage pulmonary hypertension. She has been an active member of the Pulmonary Hypertension Association (PHA) and is currently on the Board of Trustees of the PHA, Immediate past Chair of the Scientific Leadership Council of the PHA, past Chair of the Review Committee for PHCC PH Center Accreditation Program, and past Editor-in Chief of the medical journal Advances in Pulmonary Hypertension. Dr. Rosenzweig was recently appointed to be on the Scientific Board of the World Symposium on PH Association.