Physician’s Profile
Profile image of John M. Karamichalis, MD

John M. Karamichalis, MD

Cardiac Surgery
Pediatric/Congenital Cardiac Surgery
Thoracic and Cardiac Surgery

Dr. Karamichalis is an experienced pediatric heart surgeon who graduated from the University of Oxford Medical School in England and completed his Congenital Cardiac Surgery training at the University of Colorado Children's Hospital (clinical training) and Boston Children's Hospital (research training).

Before joining CUIMC, he served on the faculty at the University of Tennessee Health Science Center and Le Bonheur Children's Hospital, and prior to that, the University of California San Francisco.

He is certified in Cardiac and Thoracic Surgery by the American Board of Thoracic Surgery with subspecialty certification in Congenital Cardiac Surgery. He is a Fellow of the American College of Surgeons and member of the Royal College of Surgeons of England, and recipient of many awards throughout his career.


Nathan M, Karamichalis JM, Liu H, Gauvreau K, Colan S, Pigula F, Fynn-Thompson F, Saia M, Emani S, Baird C, Mayer JE, del Nido PJ. Technical Performance Scores are strongly associated with Early Mortality, Postoperative Adverse Events and Length of Stay – Analysis of Consecutive Discharges over 2 years. J Thorac Cardiovasc Surg 2014;147(1):389-396.

Nathan M, Karamichalis JM, Liu H, Emani S, Baird C, Pigula F, Colan S, Thiagarajan R, Bacha E, del Nido PJ. Surgical Technical Performance Scores are predictors for late mortality and unplanned reinterventions in infants after cardiac surgery. J Thorac Cardiovasc Surg 2012;144:1095-1101.

Karamichalis JM, Colan SD, Nathan M, Pigula FA, Baird C, Marx G, Emani SM, Geva T, Fynn-Thompson FE, Liu H, Mayer JE Jr, del Nido PJ. Technical Performance Scores in Congenital Cardiac Operations: A Quality Assessment Initiative. Ann Thorac Surg 2012;94:1317-23.

Nathan M, Karamichalis JM, Liu H, del Nido P, Pigula F, Thiagarajan R, Bacha EA: Intra-operative adverse events can be compensated in infants after cardiac surgery: A prospective study. J Thorac Cardiovasc Surg 2011;142:1098-1107.

Karamichalis JM, del Nido PJ, Thiagarajan RR, Liu H, Jenkins KJ, Gauvreau K, Pigula FA, Fynn-Thompson FE, Emani SM, Mayer JE Jr, Bacha EA. Early post-operative severity of illness predicts outcomes following the stage I Norwood procedure Ann Thorac Surg 2011;92:660-665.