Profile image of Marco  Bertucci Zoccali, MD, FACS, FASCRS

Marco Bertucci Zoccali, MD, FACS, FASCRS


Anorectal Disorder
Colon Cancer
Colon and Rectal Surgery
Inflammatory Bowel Disease (IBD)
Pelvic Floor Disorders
Rectal Cancer
Rectal Prolapse


Marco B. Zoccali is a minimally invasive surgeon with extensive expertise in the treatment of the broad range of colorectal diseases including IBD, colon and rectal cancers, and benign colorectal diseases.

He received his medical degree at the Catholic University in Rome, Italy where he also completed his surgical training. He then came to the USA where he did a Minimally Invasive Gastrointestinal Surgery Fellowship at the University of Chicago followed by a surgical residency at Weill Cornell Medical Center. He then completed his Colon and Rectal Surgery Fellowship at the University of Chicago.

Although committed to managing the entire spectrum of pathologies that can affect the lower intestinal tract, his personal interest lies mostly in minimally invasive approaches to colorectal conditions – including the robotic platform – and the management of inflammatory bowel diseases.

Beyond his clinical practice, Dr. Zoccali is also a prolific researcher. He has published more than 50 articles in major surgical journals including The Journal of The American College of Surgeons, The British Journal of Surgery and Inflammatory Bowel Disease, and has contributed to several book chapters.


Inflammatory Bowel Disease
Minimally invasive surgery


Bertucci Zoccali, M., Moallem, D.H., Park, H., Uhlemann, A.-C., Church, J.M., Kiran, R.P. Role of Microbiome in the Outcomes Following Surgical Repair of Perianal Fistula: Prospective Cohort Study Design and Preliminary Results (2023) World Journal of Surgery, 47 (12), pp. 3373-3379. 

Bertucci Zoccali, M., Minko, E., Betcher, M. Laparoscopic Total Abdominal Colectomy With End Ileostomy (2023) Diseases of the Colon and Rectum, 66 (11), pp. E1131-E1132.

Bertucci Zoccali, M., Church, J.M., Kiran, P.R. Partial Delorme procedure for the management of recurrent isolated posterior wall prolapse after robotic ventral mesh rectopexy for rectal prolapse (2023) Techniques in Coloproctology, 27 (10), pp. 957-958. 

Bertucci Zoccali, M., Jabi, O. Robotic assisted removal of migrated intrauterine device (2023) Colorectal Disease, 25 (8), pp. 1718-1719.

Kurtzman, J.T., Sayegh, C., Mendonca, S., Chowdhury, M., Kerr, P., Pagan, C., Zoccali, M.B., Brandes, S.B. Is colorectal mucosa a reasonable graft alternative to buccal grafts for urethroplasty?: A comparison of graft histology and stretch (2023) International Braz J Urol, 49 (1), pp. 41-49. 

Bertucci Zoccali, M., Vila-Reyes, H. Laparoscopic Sigmoid Colectomy for Diverticular Disease: Clinical Scenarios and Technical Options (2022) Diseases of the Colon and Rectum, 65 (2), pp. E78-E79.

Bhama, A.R., Zoccali, M.B., Chapman, B.C., Davids, J.S., Eisenstein, S., Fish, D.R., Sherman, K.L., Simianu, V.V., Zaghiyan, K.N. Practice Variations in Chemodenervation for Anal Fissure among American Society of Colon and Rectal Surgeons Members (2021) Diseases of the Colon and Rectum, 64 (10), pp. 1167-1171.

Bertucci Zoccali, M., Fichera, A. Anastomotic Techniques for Abdominal Crohn's Disease: Tricks and Tips (2021) Journal of Laparoendoscopic and Advanced Surgical Techniques, 31 (8), pp. 861-866.

Zoccali, M.B., Kuritzkes, B.A., Hyde, G.A. Laparoscopic Fecal Diversion (Loop Sigmoid Colostomy) (2020) Diseases of the Colon and Rectum, 63 (10), pp. E521-E522.

Zoccali, M.B., Hyman, N.H., Skowron, K.B., Rubin, M., Cannon, L.M., Hurst, R.D., Umanskiy, K., Rubin, D.T., Shogan, B.D. Exposure to Anti-tumor Necrosis Factor Medications Increases the Incidence of Pouchitis after Restorative Proctocolectomy in Patients with Ulcerative Colitis (2019) Diseases of the Colon and Rectum, 62 (11), pp. 1344-1351.

Vigorita, V., Bertucci Zoccali, M., Martinez Miguez, M., Ave Seijas, M.J., Fernandez Martin, R., Casal Nuñez, E.J., De Castro Parga, G. Giant intracystic (encysted) papillary carcinoma of the breast (2015) Breast Journal, 21 (5), pp. 555-557.

Schwartz, D.A., Ghazi, L.J., Regueiro, M., Fichera, A., Zoccali, M., Ong, E.M.W., Mortelé, K.J. Guidelines for the multidisciplinary management of Crohn's perianal fistulas: Summary statement (2015) Inflammatory Bowel Diseases, 21 (4), pp. 723-730. 

Fichera, A., Zoccali, M. Guidelines for the Surgical Treatment of Crohn's Perianal Fistulas (2015) Inflammatory Bowel Diseases, 21 (4), pp. 753-758. 

Vigorita, V., Ausania, F., Bertucci Zoccali, M., Alvarez, C.F., Nadal, B.D.U., Nuñez, J.E.C. Small bowel intussusception secondary to metastatic melanoma 15 years after complete excision of the primary tumor (2015) International Journal of Surgery Case Reports, 6, pp. 26-28.

Zoccali, M.B., Biondi, A., Krane, M., Kueberuwa, E., Rizzo, G., Persiani, R., Coco, C., Hurst, R.D., D'Ugo, D., Fichera, A. Risk factors for wound complications in patients undergoing primary closure of the perineal defect after total proctectomy (2014) International Journal of Colorectal Disease, 30 (1), pp. 87-95.

Pedroso, J.A., Paola Salerno, M., Spagnoletti, G., Bertucci-Zoccali, M., Zaccone, G., Bianchi, V., Romagnoli, J., Citterio, F. Elderly kidney transplant recipient with intermittent fever: A case report of leishmaniasis with acute kidney injury during liposomal amphotericin B therapy (2014) Transplantation Proceedings, 46 (7), pp. 2365-2367. 

Allaix, M.E., Krane, M.K., Zoccali, M., Umanskiy, K., Hurst, R., Fichera, A. Postoperative portomesenteric venous thrombosis: Lessons learned from 1,069 consecutive laparoscopic colorectal resections (2014) World Journal of Surgery, 38 (4), pp. 976-984. 

Persiani, R., Biondi, A., Gambacorta, M.A., Bertucci Zoccali, M., Vecchio, F.M., Tufo, A., Coco, C., Valentini, V., Doglietto, G.B., D'Ugo, D. Prognostic implications of the lymph node count after neoadjuvant treatment for rectal cancer (2014) British Journal of Surgery, 101 (2), pp. 133-142. 

Zoccali, M., Patti, M.G. Esophageal achalasia (2013) Mastery of Endoscopic and Laparoscopic Surgery: Fourth Edition, pp. 146-153.

Krane, M.K., Allaix, M.E., Zoccali, M., Umanskiy, K., Rubin, M.A., Villa, A., Hurst, R.D., Fichera, A. Does morbid obesity change outcomes after laparoscopic surgery for inflammatory bowel disease? review of 626 consecutive cases (2013) Journal of the American College of Surgeons, 216 (5), pp. 986-996. 

Krane, M.K., Allaix, M.E., Zoccali, M., Umanskiy, K., Rubin, M.A., Villa, A., Hurst, R.D., Fichera, A. Preoperative infliximab therapy does not increase morbidity and mortality after laparoscopic resection for inflammatory bowel disease (2013) Diseases of the Colon and Rectum, 56 (4), pp. 449-457.

Bello, B., Zoccali, M., Gullo, R., Allaix, M.E., Herbella, F.A., Gasparaitis, A., Patti, M.G. Gastroesophageal Reflux Disease and Antireflux Surgery-What Is the Proper Preoperative Work-up? (2013) Journal of Gastrointestinal Surgery, 17 (1), pp. 14-20.

Fichera, A., Zoccali, M., Kono, T. Antimesenteric Functional End-to-End Handsewn (Kono-S) Anastomosis (2012) Journal of Gastrointestinal Surgery, 16 (7), pp. 1412-1416. 

Holder-Murray, J., Zoccali, M., Hurst, R.D., Umanskiy, K., Rubin, M., Fichera, A. Totally laparoscopic total proctocolectomy: A safe alternative to open surgery in inflammatory bowel disease (2012) Inflammatory Bowel Diseases, 18 (5), pp. 863-868.

Zoccali, M., Fichera, A. Minimally invasive approaches for the treatment of inflammatory bowel disease (2012) World Journal of Gastroenterology, 18 (46), pp. 6756-6763.

Biondi, A., Zoccali, M., Costa, S., Troci, A., Contessini-Avesani, E., Fichera, A. Surgical treatment of ulcerative colitis in the biologic therapy era (2012) World Journal of Gastroenterology, 18 (16), pp. 1861-1870. 

Fichera, A., Zoccali, M. Single-incision laparoscopic total abdominal colectomy for refractory ulcerative colitis (2012) Surgical Endoscopy, 26 (3), pp. 862-868.…

Zoccali, M., Fichera, A. Role of radiation in intermediate-risk rectal cancer (2012) Annals of Surgical Oncology, 19 (1), pp. 126-130. 

Zoccali, M., Hart, J., Fichera, A. Image of the month (2012) Archives of Surgery, 147 (1), pp. 93+94.

Gullo, R., Zoccali, M., Frim, D.M., Skelly, C., Fichera, A. A large pelvic mass in a 39-year-old man (2011) Updates in Surgery, 63 (4), pp. 293-296.

Zoccali, M., Fichera, A. Current laparoscopic management of inflammatory bowel disease (2011) Minerva Chirurgica, 66 (6), pp. 589-601.

Fichera, A., Zoccali, M., Felice, C., Rubin, D.T. Total Abdominal Colectomy for Refractory Ulcerative Colitis. Surgical Treatment in Evolution (2011) Journal of Gastrointestinal Surgery, 15 (11), pp. 1909-1916. 

Zoccali, M., Krane, M., Fichera, A. Updates on rectal cancer (2011) Current Colorectal Cancer Reports, 7 (3), pp. 200-210.

Zoccali, M., Cipriani, N., Fichera, A., Turner, J.R., Krane, M. Acute Appendicitis Secondary to a Granular Cell Tumor of the Appendix in a 19-Year-Old Male (2011) Journal of Gastrointestinal Surgery, 15 (8), pp. 1482-1485. 

Fichera, A., Zoccali, M., Gullo, R. Single Incision ("Scarless") Laparoscopic Total Abdominal Colectomy with End Ileostomy for Ulcerative Colitis (2011) Journal of Gastrointestinal Surgery, 15 (7), pp. 1247-1251.

Pacelli, F., Rosa, F., Marrelli, D., Pedrazzani, C., Bossola, M., Zoccali, M., Marchet, A., Cosmo, M.D., Roata, C., Graziosi, L., Cavazzoni, E., Covino, M., D'Ugo, D., Roviello, F., Nitti, D., Doglietto, G.B. Do perioperative blood transfusions influence prognosis of gastric cancer patients? Analysis of 927 patients and interactions with splenectomy (2011) Annals of Surgical Oncology, 18 (6), pp. 1615-1623. 

Biondi, A., Persiani, R., Cananzi, F., Zoccali, M., D'Ugo, D. Prognostic value of preoperative staging in gastric cancer (2011) Annals of Surgery, 253 (4), p. 838. 

Biondi, A., Persiani, R., Vigorita, V., Cananzi, F., Zoccali, M., D'Ugo, D. Gastrointestinal: Videocapsule retention: Rationale for surgical indication (2011) Journal of Gastroenterology and Hepatology (Australia), 26 (3), pp. 608-608.

D'Ugo, D., Persiani, R., Zoccali, M., Cananzi, F., Vigorita, V., Mazzeo, P., Tufo, A., Biondi, A. Surgical issues after neoadjuvant treatment for gastric cancer (2010) European Review for Medical and Pharmacological Sciences, 14 (4), pp. 315-319.

Biondi, A., Persiani, R., Cananzi, F., Zoccali, M., Tufo, A., D'Ugo, D. Limited lymph node dissection and metastatic lymph node ratio: A wave of trust (2010) World Journal of Surgery, 34 (5), pp. 1136-1137.

Biondi, A., Persiani, R., Cananzi, F., Zoccali, M., Vigorita, V., Tufo, A., D'Ugo, D. R0 resection in the treatment of gastric cancer: Room for improvement (2010) World Journal of Gastroenterology, 16 (27), pp. 3358-3370. 

Biondi, A., Persiani, R., Zoccali, M., Rausei, S., Cananzi, F., D'Ugo, D. Harlequin Syndrome (2009) Annals of Thoracic Surgery, 88 (1), p. 304. 

Persiani, R., Antonacci, V., Biondi, A., Rausei, S., La Greca, A., Zoccali, M., Ciccoritti, L., D'Ugo, D. Determinants of Surgical Morbidity in Gastric Cancer Treatment (2008) Journal of the American College of Surgeons, 207 (1), pp. 13-19. 

Biondi, A., Persiani, R., Rausei, S., Cananzi, F.C.M., Zoccali, M., Vecchioli, A., D'Ugo, D. Large bowel auto-amputation and passage of a colon 'cast' after left hemicolectomy [1] (2008) International Journal of Colorectal Disease, 23 (5), pp. 551-552. 

Biondi, A., Rausei, S., Cananzi, F.C.M., Zoccali, M., D'Ugo, S., Persiani, R. Surgical anatomy of the anterior mediastinum [Anatomia chirurgica del mediastino anteriore] (2007) Annali Italiani di Chirurgia, 78 (5), pp. 351-353. 

Biondi, A., Rausei, S., Zoccali, M., Vigorita, V., Persiani, R. Postoperative care after esophagectomy: The surgeon's view (2005) Rays - International Journal of Radiological Sciences, 30 (4), pp. 299-307.

Persiani, R., D'Ugo, D., Biondi, A., Rausei, S., Vigorita, V., Zoccali, M., Picciocchi, A. T-downstaging after neoadjuvant chemotherapy in locally advanced gastric carcinoma [T-downstaging dopo chemioterapia neoadiuvante nel carcinoma gastrico localmente avanzato.] (2005) I supplementi di Tumori : official journal of Società italiana di cancerologia ... [et al.], 4 (3), pp. S88.