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Prospective, Multi-Center, Open Label, Pilot Study of Safety and Efficacy of Triple Anti-Viral Therapy with Pegylated Interferon, Ribavirin, and Boceprevir in Patients with Genotype 1 Chronic HCV with End Stage Renal Disease

… The purpose of the study is to assess the safety and efficacy of triple therapy with pegylated interferon (P-IFN), ribavirin and boceprevir in patients with genotype 1 chronic Hepatitis C Virus (HCV) infection and end stage renal disease (ESRD) on hemodialysis (HD). …

Last Modified: 02/13/2023 - 21:06

Multicenter, Randomized Phase 2B Study to Evaluate the Efficacy, Safety, and Tolerability of OCR-002 (Ornithine Phenylacetate) in Hospitalized Patients with Cirrhosis and Associated Hyperammonemia with an Episode of Hepatic Encephalopathy (STOP-HE)

… Phase 2B Study to Evaluate the Efficacy, Safety, and Tolerability of OCR-002 (Ornithine Phenylacetate) in Hospitalized Patients with Cirrhosis and Associated Hyperammonemia with an Episode of Hepatic …

Last Modified: 02/13/2023 - 21:06

A Phase 1 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839, as a Single Agent and in Combination with Standard Chemotherapy in Patients with Advanced/Treatment-Refractory Solid Tumors

… that can be given without causing severe side effects and to look for early signs of clinical activity. CB-839 … means that has not been approved by the United States Food and Drug Administration (FDA) for use outside of research … treatment. In this study, biomarkers found in tumor tissue and blood will be collected and tested to see if the study …

Last Modified: 02/13/2023 - 21:06

After Breast Cancer Twice in One Year, Early Detection and New Radiation Therapy Made All the Difference

… tried to avoid. She got one every year without fail and scheduled her annual wellness appointments to fall six … every six months.” Karin has large breasts, they’re dense, and her great aunt died of breast cancer fairly young. She … not shocked or hysterical or any of those things.” This visit happened to be her first time getting a 3D mammogram, a …

Last Modified: 11/09/2023 - 12:03

25 Years After Heart and Double Lung Transplant—Sean Recounts His Surgery During the Blizzard of ‘93

… to month pursuit, a hemorrhage could occur at any moment, and blood clots blocked his lungs intermittently throughout … his struggling heart. “A lot of people would sit home and wait for the inevitable, where I never thought that way,” says Sean. “I just kept going and doing a lot of crazy stuff, motorcycle racing, car …

Last Modified: 02/19/2023 - 13:12

Interventional Endocrinology: What to Expect for Radiofrequency Ablations And Ethanol Ablations Of Thyroid Nodules Or Lymph Nodes

… thinning medications such as aspirin, coumadin, Xarelto, and Eliquis be safely stopped five days prior to the … unless directed otherwise by your doctor. You may eat and drink normally up until your appointment.  Please note … exacerbate some medical conditions such as acid reflux, and therefore, it may be more comfortable not to eat a meal …

Last Modified: 11/06/2025 - 15:19

A Multicenter “Ablate and Resect” Study of Novilase Interstitial Laser Therapy for the Ablation of Small Breast Cancers

… The purpose of the research is to study and report the effects of Novilase breast therapy for small … ablation procedure takes place in an outpatient setting, and is typically completed in 30-60 minutes. … A Multicenter “Ablate and Resect” Study of Novilase Interstitial Laser Therapy for …

Last Modified: 02/13/2023 - 21:05

A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid Tumors

… is an antibody that targets CEA on the tumor cells and may activate the immune system in targeting cancer cells. … will also explore how the study drug works in the body and on the tumor. The study also wants to find out if … A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid …

Last Modified: 02/19/2023 - 13:11

A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients with Advanced Pancreatic Neuroendocrine Tumors

… is a Phase II study that will compare the effects, good and/or bad, of temozolomide versus temozolomide plus … alone or temozolomide andcapecitabine. Temozolomide and capecitabine are chemotherapy drugs, which have benefited … A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients with Advanced Pancreatic …

Last Modified: 02/13/2023 - 21:06

Monitoring the long term safety and efficacy of Novilase breast interstitial laser therapy in real world application

… To assess the assess the potential advantages and disadvantages of interstitial laser therapy (ILT) … Monitoring the long term safety and efficacy of Novilase breast interstitial laser therapy in …

Last Modified: 02/13/2023 - 21:06

Changes in Insulin Sensitivity, Appetite Hormones, Body Composition, and Energy Expenditure after Weight Loss induced by Bariatric Surgery

… insulin sensitivity, appetite hormones, metabolic rate and body composition before and after weight loss induced by gastric bypass, gastric … compensation for participants’ time (up to $150 for each visit) and travel (up to $20 per visit). The total amount of …

Last Modified: 02/13/2023 - 21:04

Proactive Activists: Ralph and Mariann Cheney Receive the 2015 Surgery of the Alimentary Tract (SSAT) Public Service Award

… The last time we checked in with Ralph and Mariann Cheney, they were recognized with the Pancreatic … community, they continue to demonstrate their passion and dedication for the bettering of society. Now, five years … Service Award for their continued advocacy, support, and leadership within the pancreatic cancer community. Ralph …

Last Modified: 02/19/2023 - 13:10

At-Home Thyroid Testing Kits: What We Know...and What We Don’t. An Interview with Dr. Hyesoo Lowe

… across the globe.  People are working, socializing, and even visiting their doctors from home.  As people become more and more comfortable with the idea of receiving their health … Now that the indefinite future creates extra burden and anxiety when it comes to venturing outside, are these …

Last Modified: 02/23/2023 - 18:02

Effect of Preoperative Breast MRI on Surgical outcomes, Costs and Quality of life of Women with Breast Cancer

… of Preoperative Breast MRI on Surgical outcomes, Costs and Quality of life of Women with Breast Cancer …

Last Modified: 02/13/2023 - 21:06

A Randomized, Open-Label, Multicenter, Controlled Study to Assess Safety and Efficacy of ELAD in Subjects with Acute Alcoholic Hepatitis (AAH)

… The primary objective of the study is to evaluate safety and efficacy of ELAD® with respect to overall survival (OS) … to determine the proportion of survivors at Study Days 28 and 91. Exploratory objectives are to evaluate the ability of … (MELD)-based time to progression (TTP) up to Study Day 91, and the proportion of progression-free survivors (PFS) up to …

Last Modified: 02/13/2023 - 21:06

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