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THRIVE: Thymira Indeterminate FNA Validation: A Validation study to establish the specificity and sensitivity of Thymira diagnostic test for patients with Indeterminate FNAs versus the standard pathological examination

… A Validation study to establish the specificity and sensitivity of Thymira diagnostic test for patients with …

Last Modified: 02/13/2023 - 21:06

A Multi-Center, Randomized, Prospective, Open-Label Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Hepatitis C Immune Globulin Intravenous (Human), Civacir, in Orthotopic Liver Transplant Recipients

… The purpose of this study is to test the safety and efficacy of Civacir® to prevent the recurrence of … Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Hepatitis C Immune Globulin …

Last Modified: 02/13/2023 - 21:06

A Prospective, Single-blind, Randomized, Phase III Study to Evaluate the Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) as an Adjunct to Hemostasis During Parenchymous Tissue Open Surgeries

… This study is designed to assess the safety and efficacy of fibrin sealant (FS) Grifols in patients … to become familiar with the application of FS Grifols and a Primary Part (II) to assess the safety and efficacy of FS Grifols. In both parts of the study, … Randomized, Phase III Study to Evaluate the Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) as an …

Last Modified: 02/13/2023 - 21:06

A randomized, open-label, multicenter trial to determine safety and efficacy of eculizumab in the prevention of antibody mediated rejection (AMR) in living donor kidney transplant recipients requiring desensitization therapy

… purpose of the study is to determine if eculizumab is safe and could be used following desensitization therapy to … open-label, multicenter trial to determine safety and efficacy of eculizumab in the prevention of antibody …

Last Modified: 02/13/2023 - 21:04

A 24 month, randomized, controlled, study to evaluate the efficacy and safety of concentration-controlled everolimus plus reduced tacrolimus compared to standard tacrolimus in recipients of living donor liver transplants

… The purpose of this trial is to demonstrate the efficacy and safety of everolimus in combination with reduced … randomized, controlled, study to evaluate the efficacy and safety of concentration-controlled everolimus plus …

Last Modified: 02/13/2023 - 21:06

Use of Endoscopically Delivered Radiofrequency Ablation for the Treatment of Patients Who Have Undergone Roux-en-Y Gastric Bypass and Have Failed to Achieve/ Maintain Satisfactory Excess Body Weight Loss

… of Patients Who Have Undergone Roux-en-Y Gastric Bypass and Have Failed to Achieve/ Maintain Satisfactory Excess Body …

Last Modified: 02/13/2023 - 21:04

A Phase 3b study to evaluate the long-term outcomes following treatment with Abbvie DAAs and with or without Ribavirin (RBV) in adults with genotype 1 Chronic Hepatitis C Virus (HCV) Infection

… long-term outcomes following treatment with Abbvie DAAs and with or without Ribavirin (RBV) in adults with genotype 1 …

Last Modified: 02/13/2023 - 21:06

Phase II Open-Label, Single-Center Study Evaluating Safety and Efficacy of Pembrolizumab Following Induction with the Hypomethylating Agent Azacitidine in Patients with Advanced Pancreatic Cancer After Failure of First-Line Therapy

… Phase II Open-Label, Single-Center Study Evaluating Safety and Efficacy of Pembrolizumab Following Induction with the …

Last Modified: 02/13/2023 - 21:07

A Study of PEGylated Recombinant Human Hyaluronidase in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Participants With Hyaluronan-High Stage IV Previously Untreated Pancreatic Ductal Adenoca

… The purpose of this study is to compare the efficacy and safety of PEGPH20 combined with nab-paclitaxel & … study is to compare the efficacy (how well the drug works) and safety (how well the drug is tolerated) of the study … with Placebo (normal saline, that is, a mixture of salt and water with an amount of salt similar to body fluids) in …

Last Modified: 02/13/2023 - 21:07

A 24-month, multi-center, single arm, prospective study to evaluate renal function, efficacy, safety and tolerability of everolimus in combination with reduced exposure cyclosporine or tacrolimus in paediatric liver transplant : CRAD001H2305

… is designed to assess the evolution of renal function and to collect efficacy, safety, and tolerability data of everolimus in co-exposure with … study to evaluate renal function, efficacy, safety and tolerability of everolimus in combination with reduced …

Last Modified: 02/13/2023 - 21:06

A Phase 1, Open-Label, Dose Escalation Study of MGA271 in Combination with Ipilimumab in Patients with B7-H3-Expressing Melanoma, Squamous Cell Cancer of the Head and Neck or Non Small Cell Lung Cancer

… purpose of this study is to test the safety, tolerability, and most effective dose of MGA271 in combination with … that regulates new medicines, including the US Food and Drug Administration (FDA). Ipilimumab is approved by the … use in melanoma patients, but it is experimental for NSCLC and SCCHN patients. This is the first time that MGA271 and …

Last Modified: 02/13/2023 - 21:06

A Randomized, Double-blind, Placebo-controlled, Dose-ranging, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) Tablets for the Prevention of Complications in Subjects With Early Decompensated Liver Cirrhosis

… Dose-ranging, Multicenter Study to Assess the Efficacy and Safety of Rifaximin Soluble Solid Dispersion (SSD) …

Last Modified: 02/13/2023 - 21:06

A Phase 2, Multicenter, Open-Label Study to Investigate the Safety and Efficacy of Sofosbuvir/Ledipasvir Fixed-Dose Combination + Ribavirin Administered in Subjects Infected with Chronic HCV who have Advanced Liver Disease or are Post-Transplant

… 2, Multicenter, Open-Label Study to Investigate the Safety and Efficacy of Sofosbuvir/Ledipasvir Fixed-Dose Combination …

Last Modified: 02/13/2023 - 21:06

PRO 02/ML28897 MY PATHWAY STUDY: An Open-Label Phase IIA Study Evaluating Trastuzumab/ Pertuzumab, Erlotinib, Vermurafenib, and Vismodegib in Patients Who Have Advanced Solid Tumors with Mutations or Gene Expression Abnormalities Predictive of Response to

… that will convey clinical benefit are not available, and in whom a trial of targeted therapy is considered the … works to help stop this abnormal growth. Trastuzumab and pertuzumab are drugs that target the HER2 receptor, a … plays an important role in the cell’s ability to grow and multiply as a cancer cell. By blocking the hedgehog …

Last Modified: 02/13/2023 - 21:06

How to Tackle a Farmers Market

… best way to ensure that what you’re buying is seasonal, fresh, and local. Not only do you get better quality food, but … area . Put together a rough list of items you’d like to buy, but stay flexible since you never know what will be …

Last Modified: 02/23/2023 - 18:00

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