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Investigation of Calcium/Calmodulin Dependent Protein Kinase II (CaMKII) activity in human liver tissue.
… The goal of this research is to gain information whether a calcium sensing enzyme … This research will supplement additional information about the pathogenesis of insulin resistance associated with … Investigation of Calcium/Calmodulin Dependent Protein Kinase II (CaMKII) …
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Randomized, placebo-controlled trial of netazepide (YF476), a gastrin receptor antagonist, in Barrett’s esophagus
… The purpose of this study is to determine whether the drug netazepide may potentially be able to lower the risk … Randomized, placebo-controlled trial of netazepide (YF476), a gastrin receptor antagonist, in …
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Post-Approval Study Of Transcarotid Artery Revascularization In Patients With Significant Carotid Artery Disease
… Study Overview The ROADSTER 2 Study is an open label, single arm, multi-center post-approval Study for the treatment of patients at high risk for adverse events from carotid … Post-Approval Study Of Transcarotid Artery Revascularization In Patients With …
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Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients with Pathologic Nipple Discharge
… The primary goal is to determine whether retrieval of a solitary papilloma can … open surgical excision. Secondary aim will be to evaluate the therapeutic success of this procedure. … Feasibility and Therapeutic Efficacy of Ductoscopic Papilloma Extraction in Patients with …
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Prospective Registry Of MammaPrint in Breast Cancer Patients with an Intermediate Recurrence Score (PROMIS)
… This is a prospective study that will assess the impact of … Prospective Registry Of MammaPrint in Breast Cancer Patients with an Intermediate …
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Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy for Adrenocortical Carcinoma
… carcinoma (ACC) evaluable by CT imaging with the majority of disease confined to the peritoneal cavity and surgically resectable to a residual … Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal …
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Relative Abundance and Spatial Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease
… To establish the structure, abundance and localization of lipids and proteins within human liver biopsies and to … Relative Abundance and Spatial Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease …
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After Breast Cancer Twice in One Year, Early Detection and New Radiation Therapy Made All the Difference
… wellness appointments to fall six months in between. The way she puts it, “somebody was squeezing my breasts every … has large breasts, they’re dense, and her great aunt died of breast cancer fairly young. She has other high-risk … 50! Don’t I get a couple more years?” says Karin. “But it is what it is, I was not shocked or hysterical or any of …
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A Phase I Study of IHD305 in Patients with Advanced Malignancies that Harbor IDH1R132 Mutations
… The primary purpose of this research study is to assess how safe and well tolerated the study drug, IDH305, is when given to patients who have … A Phase I Study of IHD305 in Patients with Advanced Malignancies that Harbor …
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A randomized, double-blind, placebo-controlled, phase II study of sorafenib in subjects with hepatopulmonary syndrome
… he main purpose of this clinical trial is to determine the safety and effects of the study drug, … double-blind, placebo-controlled, phase II study of sorafenib in subjects with hepatopulmonary syndrome …
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A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV (POLT-HCV-SVR)
… A Multicenter, Double-Blind, Sponsor-Open Trial of IDN- 6556 in Subjects Who had Hepatitis C Virus (HCV) … Virologic Response Following anti-HCV Therapy This is a double-blind, multicenter study involving patients with … IDN-6556 is better than placebo in reversing or stopping the progression of the damage to the new liver caused by HCV. …
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Simtuzumab (GS-6624) in Treatment of Advanced Liver Fibrosis But Not Cirrhosis Secondary to NASH
… Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of GS-6624, a Monoclonal Antibody Against Lysyl Oxidase-Like … whether simtuzumab (formerly referred to as GS-6624) is effective at preventing the histologic progression of … Simtuzumab (GS-6624) in Treatment of Advanced Liver Fibrosis But Not Cirrhosis Secondary to NASH …
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Prospective, Multi-Center, Open Label, Pilot Study of Safety and Efficacy of Triple Anti-Viral Therapy with Pegylated Interferon, Ribavirin, and Boceprevir in Patients with Genotype 1 Chronic HCV with End Stage Renal Disease
… The purpose of the study is to assess the safety and efficacy of triple … Prospective, Multi-Center, Open Label, Pilot Study of Safety and Efficacy of Triple Anti-Viral Therapy with Pegylated Interferon, …
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Utility of [18F]-FDG PET Imaging to Distinguish Malignant from Benign Intrapapillary Mucinous Neoplasms (IPMN)
… An accurate, non-invasive method to identify malignant IPMN is needed, as endoscopic ultrasounds are invasive and … operator-dependent. PET/CT is already being utilized in the utility, management, and follow-up surveillance of pancreatic adenocarcinoma. Therefore, we are hypothesizing …
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Treatment of Breast Fibroadenoma targeted tissue with High Intensity Focused Ultrasound (HIFU): A Pivotal Multi Center Prospective Study
… The purpose of this study is to test an investigational device called the Echopulse for … pain, anxiety and discomfort permanently or during their menstrual cycle. A biopsy (using a needle to take a … Treatment of Breast Fibroadenoma targeted tissue with High Intensity …
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