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A Phase Ib/II, multicenter, open label, study of LEE011 in combination with MEK162 in adult patients with NRAS mutant melanoma
… The purpose of this protocol is to evaluate the effects of the combination of two drugs, LEE011 and … A Phase Ib/II, multicenter, open label, study of LEE011 in combination with MEK162 in adult patients with …
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A Phase III Randomized, Controlled, Superiority Study Evaluating EVARREST Fibrin Sealant Patch Versus Standard of Care Treatment in Controlling Parenchymal Bleeding During Hepatic Surgery
… To evaluate the safety and hemostatic effectiveness of EVARREST™ Fibrin Sealant Patch (EVARREST) versus standard of care treatment (SoC) in controlling parenchymal bleeding … Evaluating EVARREST Fibrin Sealant Patch Versus Standard of Care Treatment in Controlling Parenchymal Bleeding During …
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Randomized Study of Early Palliative Care Integrated With Standard Oncology Care Versus Standard Oncology Care Alone In Patients With Incurable Lung or Non- Colorectal Gastrointestinal Malignancies
… To determine the efficacy of early integrated palliative care on patient reported quality of life at 12 weeks using the FACT in patients with … Randomized Study of Early Palliative Care Integrated With Standard Oncology …
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A Phase II Randomized Multicenter Placebo- Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver Transplant (OLT) Recipients with Hepatocellular Carcinoma (HCC)
… The purpose of this study is to determine if sorafenib (sorafenib tosylate) is a safe … for liver cancer patients, but despite transplantation, the liver cancer can recur in the new, transplanted liver. It … Randomized Multicenter Placebo- Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver …
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Safety and Efficacy of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Participants With Chronic Hepatitis C and Chronic Kidney Disease (MK-5172-052) (C-SURFER)
… A Phase II/III Randomized Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172 and MK-8742 in Subjects … pharmacokinetic sampling. The primary study hypothesis is that the proportion of participants achieving a sustained … Safety and Efficacy of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Participants …
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A Long Term Follow-up Registry Study of Subjects Who Did Not Achieve Sustained Virologic Response in Gilead-Sponsored Trials in Subjects with Chronic Hepatitis C Infection
… This Registry is designed to obtain long term data on participants who have … A Long Term Follow-up Registry Study of Subjects Who Did Not Achieve Sustained Virologic Response …
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A Phase 3b study to evaluate the long-term outcomes following treatment with Abbvie DAAs and with or without Ribavirin (RBV) in adults with genotype 1 Chronic Hepatitis C Virus (HCV) Infection
… The purpose of this study is to evaluate Long-term Outcomes following treatment with … A Phase 3b study to evaluate the long-term outcomes following treatment with Abbvie DAAs …
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Prospective Randomized Double Blind Placebo Controlled Trial of Rifaximin 550mg PO Twice Daily for Three Months to Prevent Recurrent Fibrosis in Liver Transplant Recipients with Chronic Hepatitis C Virus Infection
… The purpose of this study is to determine if the administration of a poorly-absorbable antibiotic … Randomized Double Blind Placebo Controlled Trial of Rifaximin 550mg PO Twice Daily for Three Months to Prevent …
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An Expanded Access Phase 2 Study of Sofosbuvir with Ribavirin and with or without Pegylated Interferon for 24 weeks in Subjects who have undergone Liver Transplantation and Who Have Aggressive, Recurrent Hepatitis C infection
… This is a single arm, open-label study which will be opened at specific clinical sites at the request of an investigator for the treatment of individual subjects … An Expanded Access Phase 2 Study of Sofosbuvir with Ribavirin and with or without Pegylated …
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A Study of PEGylated Recombinant Human Hyaluronidase in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Participants With Hyaluronan-High Stage IV Previously Untreated Pancreatic Ductal Adenoca
… The purpose of this study is to compare the efficacy and safety of PEGPH20 combined with … A Study of PEGylated Recombinant Human Hyaluronidase in Combination …
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A 24-month, multi-center, single arm, prospective study to evaluate renal function, efficacy, safety and tolerability of everolimus in combination with reduced exposure cyclosporine or tacrolimus in paediatric liver transplant : CRAD001H2305
… This study is designed to assess the evolution of renal function and to … evaluate renal function, efficacy, safety and tolerability of everolimus in combination with reduced exposure …
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PRO 02/ML28897 MY PATHWAY STUDY: An Open-Label Phase IIA Study Evaluating Trastuzumab/ Pertuzumab, Erlotinib, Vermurafenib, and Vismodegib in Patients Who Have Advanced Solid Tumors with Mutations or Gene Expression Abnormalities Predictive of Response to
… regimens will be evaluated simultaneously in groups of patients who have advanced solid tumors that has … are not available, and in whom a trial of targeted therapy is considered the best available treatment option. Erlotinib is a targeted … with Mutations or Gene Expression Abnormalities Predictive of Response to …
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World’s Most Comprehensive Care for IBD
… Columbia’s Division of Colorectal Surgery has unmatched expertise in the surgical management of Crohn’s Disease and ulcerative … latest techniques to improve the patient’s condition and quality of life.” The Columbia team is often able to conserve …
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Pediatric Heart Valve Center
… The Pediatric Heart Valve Center at Columbia is dedicated to improving the quality of care for children and adults with congenital heart valve …
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Our Breast Programs & Services
… As a major academic facility, we stand at the forefront of medical care, patient services, and health research. We … Program for Breast Centers (NAPBC) for the high-quality care we deliver. Learn about the NAPCB center . To …
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