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Ventricular Assist Devices (VADS) And Mechanical Circulatory Support

… blood from the heart to the body. The device, which is implanted in the patient's chest, consists of an electric … back into the aorta and out to the rest of the body. This is also known as mechanical circulatory support. VADs can be … and bandage both the incision and the driveline exit site. VADS As Bridge-To-Transplantation When used as a …

Last Modified: 12/16/2025 - 16:25

Coumadin©

… What is Coumadin®? Coumadin® is an anticoagulant. It increases the time it takes for your … and hit your head. If you get a cut, hold pressure at the site—you will bleed longer than usual. If the bleeding does …

Last Modified: 06/03/2024 - 12:15

A Phase 1/1b Study of MGCD516 in Patients With Advanced Solid Tumor Malignancies

… This is a phase 1/1b research study for adults with a diagnosis of … drug called MGCD516. Investigational means that MGCD516 is not approved by the U.S. Food and Drug Administration (FDA). MGCD516 is designed to block specific tyrosine kinases, which are …

Last Modified: 02/13/2023 - 21:06

Pancreatitis Treatments

… (IV) nutrition, antibiotics, and pain medications. Surgery is sometimes needed to treat complications. Treatment for … stomach or small intestines. Sometimes enteral nutrition is contraindicated or not tolerated. Under these circumstances, parenteral (intravenous) nutrition is indicated, and is better than no nutrition. Stents The …

Last Modified: 09/24/2025 - 13:01

A Study of PEGylated Recombinant Human Hyaluronidase in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Participants With Hyaluronan-High Stage IV Previously Untreated Pancreatic Ductal Adenoca

… The purpose of this study is to compare the efficacy and safety of PEGPH20 combined … untreated pancreatic ductal adenocarcinoma. This study is for adult patients with stage IV pancreatic cancer. The purpose of the study is to compare the efficacy (how well the drug works) and …

Last Modified: 02/13/2023 - 21:07

COVID-19 Update from Dr. Smith: 3/22/20

… outside the family find value in some parts of the message is a welcome bonus, and perhaps a reminder that even Surgeons … the same issues that perplex the rest of the world. There is nothing new to report on the sobering slope of the new-case rate. Testing is still significantly limited by availability of swabs, …

Last Modified: 02/23/2023 - 18:01

Alpha-1 Antitrypsin Deficiency

… Alpha-1 antitrypsin (AAT) deficiency is an inherited condition that can cause serious lung and … of the AAT protein. Key Facts Alpha-1 antitrypsin (AAT) is one of several proteins the liver produces and releases … vulnerable to damage and harms the liver. AAT deficiency is a genetic condition, which means it is passed down from …

Last Modified: 01/12/2026 - 11:31

Hemochromatosis

… Hemochromatosis is a metabolic disease in which iron is absorbed from the digestive tract and deposited in tissues … conditions like cirrhosis and diabetes. Hemochromatosis is often an inherited condition, which means it is caused by …

Last Modified: 01/12/2026 - 11:36

Hyperthyroidism

… hormone or by release of thyroid hormone as the gland is destroyed. An overactive thyroid is the most common cause of hyperthyroidism and can be caused … known as diffuse toxic goiter or when the whole thyroid is hyperactive), toxic multinodular goiter (when more than …

Last Modified: 10/01/2025 - 12:12

Gastric Bypass Surgery

… surgeon Francisco Guzman, MD , January 2025 Gastric bypass is a surgical procedure that induces weight loss by changing … of the digestive tract. Key Facts Gastric bypass surgery is one of the most common weight loss surgeries in the United … may not be tolerated well. Complications at Reconnection Site – Long-term complications related to intestinal …

Last Modified: 11/12/2025 - 13:43

Intraoperative Radiation Therapy for Breast Cancer

… explains how Intraoperative Radiation Therapy (IORT) is administered, its potential benefits, and eligibility. Key Info IORT involves a single dose of radiation that is administered immediately after a lumpectomy. Compared with … How Intraoperative Radiation Therapy Works A lumpectomy is a common procedure for patients with early stage breast …

Last Modified: 09/22/2025 - 12:55

Angioplasty

… Angioplasty is a nonsurgical procedure to open blocked or narrowed … coronary intervention (PCI) or balloon angioplasty, it is used to treat severely blocked coronary arteries as well … through the artery to the area of blockage. The balloon is inflated, flattening the fatty deposits and widening the …

Last Modified: 12/16/2025 - 16:13

Myocarditis

… Myocarditis is an inflammation of the heart muscle, usually as a result … of the world (and previously in the United States), TB is a common cause of pericarditis. How is Myocarditis Diagnosed? Myocarditis may start with flulike …

Last Modified: 12/16/2025 - 15:28

A Phase 1 Multiple Ascending Dose Study Of DS-3032b, An Oral MDM2 Inhibitor, In Subjects With Advanced Solid Tumors Or Lymphomas

… This Phase I research study is for individuals with advanced melanoma or lymphoma. The purpose of this study is to determine and confirm the safety and tolerance of a … has been established in Part 1 dose escalation, so Part 2 is to confirm those in the intended population. DS ‐ 3032b is …

Last Modified: 02/13/2023 - 21:06

Heart Transplantation

… transplanted in humans. Today, transplantation is performed with kidneys, liver, the pancreas, lungs, the … veins, and valves of the heart. Cardiac transplantation is the surgical placement of a healthy heart from a human donor into the body of a person whose own heart is badly diseased. The procedure is also referred to as …

Last Modified: 01/26/2026 - 11:58