A Multicenter, Double-Blind, Sponsor-Open Trial of IDN- 6556 in Subjects Who had Hepatitis C Virus (HCV) Reinfection and Liver Fibrosis following Orthotopic Liver Transplantation for Chronic HCV Infection and Who Subsequently Achieved a Sustained Virologic Response Following anti-HCV Therapy

Nipple Sparing Mastectomy (NSM) entails removing all breast tissue while sparing the overlying skin envelope including the nipple areola complex (NAC). This type of mastectomy combined with immediate reconstruction leads to a postoperative breast appearing nearly identical to a pre-operative breast.

The goal of this study is to identify genes that convey susceptibility to congenital diaphragmatic hernia in humans. The identification of such genes, and examination of their structure and function, will enable a delineation of molecular pathogenesis and, ultimately, prevention or treatment of congenital diaphragmatic hernia. There are many different possible modes of inheritance for congenital anomalies, including autosomal dominant, autosomal recessive, and multifactorial.

Prospective and retrospective data collection. This protocol establishes a registry and a tissue bank, but does not dictate treatment or intervention. The objective of this investigation is to develop a comprehensive endocrine tumor tissue bank linked to a patient-level clinical history database, and to perform research on these tissues and data in order to determine factors that influence tumor growth, metastatic propensity, and prognosis of patients with endocrine tumors (thyroid, parathyroid, adrenal, and paraganglioma).

Prospective protocol assessing the safety of autologous blood transfusions following pancreatectomy for pancreatic ductal adenocarcinoma (PDAC)

This is a Phase II study that will compare the effects, good and/or bad, of temozolomide versus temozolomide plus capecitabine on advanced pancreatic neuroendocrine tumors cancer to find out which is more effective. In this study, participants will get either temozolomide alone or temozolomide andcapecitabine. Temozolomide and capecitabine are chemotherapy drugs, which have benefited some patients with pancreatic neuroendocrine tumors yet they have never been compared; both arms are considered investigational.

The incidence of thyroid cancer has increased substantially in the past several decades and is estimated to become the 3rd most common cancer in women of all ages and the 2nd most common cancer in women under age of 45 by 2019. With 5-year and 10-year survival rates reaching 95%, a relatively younger age at diagnosis, and a rising incidence of disease, a greater prevalence of thyroid cancer survivors is emerging.

To figure out the best medical follow up of patients after pancreas transplant.

The main purpose of this study is to find out whether treatment to prevent kidney rejection with belatacept in presence of Thymoglobulin induction and withdrawal of steroids will result in less delayed graft function or "sleepy kidney" after transplant than that seen in patients who get tacrolimus as their main drug to prevent rejection instead of belatacept. The investigators will also look at whether patients who get belatacept have the same, lesser or more problems that those who get tacrolimus.

The purpose of this study is to determine whether the drug netazepide may potentially be able to lower the risk of esophageal cancer in patients with Barrett’s esophagus.