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Newly Identified Cellular Markers Improve Targets for Chemotherapy in Breast Cancer Patients

… found in cancer-associated cells could make it easier for doctors to treat breast cancer, results of a new study … a 37-gene tumor-associated macrophage (TAM) signature that is found in the most aggressive breast cancer subtypes. TAMs are associated with shorter disease-specific survival, more aggressive …

Last Modified: 02/23/2023 - 18:01

Maribavir for Treatment of Resistant or Refractory CMV Infections in Transplant Recipients

… (CMV) Activity of Different Doses of Maribavir for Treatment of CMV Infections That Are Resistant or Refractory to Treatment With Ganciclovir/Valganciclovir or Foscarnet in Transplant … of different doses of maribavir administered orally for up to 24 weeks for treatment of CMV infections that are …

Last Modified: 02/13/2023 - 21:06

Thank you for contacting the Columbia Lung and Esophageal Center of NJ.

… Thank you for contacting the Columbia Lung and Esophageal Center of NJ. … feel free to call the office directly at (212) 305-3408 with any questions you may have. Please note that the … Thank you for contacting the Columbia Lung and Esophageal Center of NJ. …

Last Modified: 02/19/2023 - 13:13

A Phase 1 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839, as a Single Agent and in Combination with Standard Chemotherapy in Patients with Advanced/Treatment-Refractory Solid Tumors

… This study is being done to determine how patients with advanced or refractory solid tumors (cancer that … be given without causing severe side effects and to look for early signs of clinical activity. CB-839 blocks the … Inhibitor CB-839, as a Single Agent and in Combination with Standard Chemotherapy in Patients with …

Last Modified: 02/13/2023 - 21:06

Serum Lipopolysaccharide (LPS) Measurement to Predict Progression of Fibrosis in Liver Transplant Recipients with Hepatitis C Virus

… Progression of Fibrosis in Liver Transplant Recipients with Hepatitis C Virus. … Progression of Fibrosis in Liver Transplant Recipients with Hepatitis C Virus …

Last Modified: 02/13/2023 - 21:06

Family and Personal History of Pancreatic and Other Malignancies in Patients with Intraductal Papillary Mucinous Neoplasms

… study to determine the proportion of patients with a family history of pancreatic cancer and other … History of Pancreatic and Other Malignancies in Patients with Intraductal Papillary Mucinous Neoplasms …

Last Modified: 02/13/2023 - 21:06

Protocol for Tracking Economic Data of Subjects Participating in Protocol VTI-208

… Protocol for Tracking Economic Data of Subjects Participating in … Protocol for Tracking Economic Data of Subjects Participating in …

Last Modified: 02/13/2023 - 21:06

Post-Kidney Transplantation: Caring for Yourself After You Leave the Hospital - Part I

… Post-Kidney Transplantation: Caring for Yourself After You Leave the Hospital - Part I …

Last Modified: 02/13/2023 - 21:04

A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients with Advanced Pancreatic Neuroendocrine Tumors

… This is a Phase II study that will compare the effects, good … are chemotherapy drugs, which have benefited some patients with pancreatic neuroendocrine tumors yet they have never … cancer. Previously collected tumor tissue will be tested for certain changes to your tumor DNA. Investigators will …

Last Modified: 02/13/2023 - 21:06

The RelayBranch Trial Introduces the First Minimally-Invasive Device for Total Aortic Arch Repair

… of the Aortic Center , to discuss the new clinical trial for endovascular total aortic arch replacement—a device … replaces the entire aortic arch without opening the chest is groundbreaking. The aortic arch is the curved section of … started with one renal artery and they said, "Well if I can do one, why can't I do two? If I can do two, I can do …

Last Modified: 03/17/2025 - 15:11

A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid Tumors

… The purpose of this study is to find out which doses of the study drug are safe to give to patients with gastrointestinal (colon, liver, pancreas, stomach) solid tumors. The study drug is RO6958688. RO6958688 is an antibody that targets CEA on … A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic …

Last Modified: 02/19/2023 - 13:11

At-Home Thyroid Testing Kits: What We Know...and What We Don’t. An Interview with Dr. Hyesoo Lowe

… some questions to help clarify some pros and cons. What is your view on at-home thyroid testing kits? It depends on what you are looking for. As a screening test, home testing may be helpful for … opinion? Are you skeptical? Optimistic? Concerned? I’m cautiously optimistic. Do you see advantages? Positive …

Last Modified: 02/23/2023 - 18:02

Abc7NY—Medical Marvels: Using immunotherapy for melanoma that spread to the brain

… winter of 2013, and something felt off on that first day for Meline, chest pains surged out of nowhere. When she got … treatment that saved her life.  Dr. Carvajal says, "When I started treating melanoma ten years ago if we saw a patient … talked about cure." But with new immunotherapy drugs cure is more than just possibility. "It’s amazing! This was a …

Last Modified: 03/29/2023 - 15:19

Treatment of Breast Fibroadenoma targeted tissue with High Intensity Focused Ultrasound (HIFU): A Pivotal Multi Center Prospective Study

… The purpose of this study is to test an investigational device called the Echopulse for treatment of breast fibroadenomas in women. Fibroadenomas … to take a small piece of the lump and exam the cells) is necessary in order to be sure that the lump is benign. …

Last Modified: 02/13/2023 - 21:07

Phase I Window of Opportunity Study of Parasympathetic Stimulation with Bethanechol in Localized Pancreatic Adenocarcinoma Prior to Surgery

… Phase I Window of Opportunity Study of Parasympathetic Stimulation with Bethanechol in Localized Pancreatic Adenocarcinoma Prior …

Last Modified: 02/13/2023 - 21:07

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