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A Randomized, Phase II Trial of Intermittent Versus Continuous Dosing of Dabrafenib NSC-763760) and Trametinib (NSC-763093) in BRAFV600E/K Mutant Melanoma

… The purpose of this study is to compare any good and bad effects of receiving the drugs … the FDA for the treatment of advanced melanoma. This study is testing whether receiving dabrafenib and trametinib with a … allow the researchers to know whether a break in treatment is better, the same, or worse than continuous treatment of …

Last Modified: 02/13/2023 - 21:06

A Phase 1 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839, as a Single Agent and in Combination with Standard Chemotherapy in Patients with Advanced/Treatment-Refractory Solid Tumors

… This study is being done to determine how patients with advanced or … activity. CB-839 blocks the production of glutamate which is critical for tumor cell growth. Investigational means that … be used to detect a disease or to find out how the cancer is responding to treatment. In this study, biomarkers found …

Last Modified: 02/13/2023 - 21:06

Luona Sun, MD

… Luona Sun, MD is a board-certified breast surgeon trained in minimal … therapy and various frontline localization skills. She is also an active researcher, focusing on rare diagnoses like … coexisting cancer. One of her major research interests is in Asian American breast cancer disparities. Dr. Sun …

Last Modified: 03/05/2026 - 09:35

Call Schedule

… Frequency of call occasionally varies, but is usually every fourth day. The students on-call work with … frequently used sites, with supervision. One night call is spent in the Emergency Department where the student may … lacerations and draining minor abscesses. Each team is assigned a call room in: Harkness Pavilion 180 Ft. …

Last Modified: 05/25/2023 - 11:46

Red Flags

… observe those around him or her in order to determine what is appropriate and expected behavior. Students are encouraged … not in ear shot of patients and families. The key issue is to behave as professionally as possible. The interaction … and you will be rewarded. Helping out your fellow student is noticed and expected. Your interns should be your friends; …

Last Modified: 05/25/2023 - 11:46

Kidney Transplant Program at Columbia

… to optimize our patients’ health and well-being.  Our team is here to be your partner every step of the way. If you are … disease (ESRD), or severe diabetes, kidney transplantation is often the most effective option to improve your quality of … University Irving Medical Center is to offer our patients unmatched surgical skill, …

Last Modified: 01/26/2026 - 11:21

Reflections of a Living Liver Donor

… watching Jen resume her life in continued good health, it is easier to write the story. Our story begins in January … on the UNOS waitlist.) In my opinion, living donation is easier on the family than waiting for a donor organ. I … because it was well managed. There was discomfort at the site of the scar, but most of my time was spent sleeping. I …

Last Modified: 02/19/2023 - 13:08

Who should avoid gluten?

… syndrome (IBS) may have NCGS. Often a low FODMAPs diet is recommended and successful at improving symptoms.  Since a low FODMAPs* diet is mostly GF, the disappearance of gastrointestinal symptoms … you may want to consider a GF diet.  Autoimmune disease is associated with a ‘leaky gut’ (scientifically speaking, …

Last Modified: 02/23/2023 - 18:00

Evaluation of Vitamin D Storage in Adipose Tissue

… the obese population. Weight loss, or bariatric surgery, is also associated with low vitamin D levels and patients who … sunlight (since vitamin D can be made in the skin when it is exposed to enough UV light). Another explanation is that vitamin D gets stored in the excess fat tissue of …

Last Modified: 02/13/2023 - 21:06

Thyroid Scar Gallery

… There will often be a little swelling around the incision site for a few weeks after the operation. A small amount of swelling is part of the normal healing process. The natural reaction to surgery is to form scar tissue that will become firmer in the first …

Last Modified: 03/26/2026 - 14:42

Bariatric Surgery for Adolescents

… A recent study from England shows that obesity in teens is a predictor of cardiovascular problems and diabetes later … or attempted suicide. Early treatment of each problem is important.” There is growing evidence, too, that bariatric surgery for obese …

Last Modified: 05/06/2024 - 14:25

Looking for patient to enroll in Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas

… If not known before, Pancreatic cancer is the third-most common cause of cancer-related death in the US. In some cases, surgical removal of the pancreas is considered the only chance for cure, but many patients are … serves as the Principal Investigator on this study and is conducting this study in collaboration with Dr. Michael …

Last Modified: 01/13/2025 - 12:06

The Kurlanksy Method: Research Explained

… This is a series about what we know and what we don’t know. Paul … with Dr. Kurlanksy: The Cost of Confusion Dr. Kurlansky is not talking about monetary cost, but the human cost. He … confusion, all of the controversy, all of the uncertainty is if you need medical care, seek medical care," says Dr. …

Last Modified: 02/23/2023 - 18:02

Anorectal Surgery FAQs

… example, ultrasound may be utilized to determine if there is anatomic sphincter damage in patients complaining of … will I have to stay in the hospital? If your surgery is for benign disease, such as hemorrhoids, fissures, or … anesthesia (anesthetic injected in and near the operative site), as well as oral pain medicines. You will be discharged …

Last Modified: 02/05/2026 - 16:03

Newly Identified Cellular Markers Improve Targets for Chemotherapy in Breast Cancer Patients

… a 37-gene tumor-associated macrophage (TAM) signature that is found in the most aggressive breast cancer subtypes. TAMs … capability to the clinic, note the researchers. “Cancer is not just a group of cells, it is an evolving  and ever changing landscape where many actors …

Last Modified: 02/23/2023 - 18:01

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