Physician’s Profile
Profile image of Jonathan P. Knowles, MD

Jonathan P. Knowles, MD

Expertise:
Anal Cancer
Anal Fissures
Anal Fistula
Colon Cancer
Colon and Rectal Surgery
Constipation
Diverticulitis
Hemorrhoids
Inflammatory Bowel Disease (IBD)
Pelvic Floor Disorders
Rectal Cancer
Rectal Prolapse
About:

Dr Jonathan Knowles is a surgical associate/advanced clinical fellow in Colorectal Surgery. He completed his medical training at University College London in 2000 and then trained in general and colorectal surgery. Since 2013 he worked as a colorectal surgeon at the Royal Free Hospital in London.

Dr Knowles has expertise in minimally invasive and open colorectal surgical procedures as well as in anorectal operations. This includes a wide spectrum of colorectal conditions including inflammatory bowel disease, colon and rectal cancer, diverticular disease and anorectal disorders.

Dr Knowles completed a Masters in Surgical Science and is a Fellow of the Royal College of Surgeons (2012).

At New York-Presbyterian/Columbia University, Dr Knowles works collaboratively with Dr Pokala Ravi Kiran obtaining additional exposure to complex and reoperative colorectal surgery.

Publications:

A case series of anal melanoma including the results of treatment with imatinib in selected patients. Authors: J. Knowles*, A. C. Lynch, S. K. Warrier, M. Henderson, A. G. Heriot. Colorectal Disease 2 September 2016

Endothelin-1 stimulates colorectal cancer adjacent fibroblasts. Knowles J*, Taylor I, Winslet M, Abraham D, Loizidou M. Int. J. Cancer 2012: 130; 1264-1272

Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines. K. Grant, J. Knowles, K. Dawas, G. Burnstock, I. Taylor, M. Loizidou. BJS 2007: 94; 1, 106-112

Title: Impact of an enhanced recovery after surgery (ERAS) pathway on colorectal surgery patients managed with perioperative Alvimopan. Accepted for eposter presentation ASCRS May 2022.

Title: Significant negative effect of previous abdominal surgery on outcomes after colorectal resection. Accepted for eposter presentation ASCRS May 2022.