Physician’s Profile

Adam D. Griesemer, MD

Surgical Director, Pediatric Liver Transplantation
Surgical Director, Living Donor Liver Transplantation-Columbia Campus
Director, Large Animal Xenotransplantation Laboratory, Columbia Center for Translational Immunology
Expertise: 
Abdominal Organ Transplant, Pediatric
Abdominal Organ Transplantation
Hepatobiliary Surgery
Liver & Abdominal Transplant Surgery
Liver Transplant
Liver Transplant, Pediatric
Living Donor Liver Surgery
Living Donor Transplantation
Minimally Invasive Liver Surgery
Organ Transplant, Pediatric
Pediatric Transplant Surgery
Portal Hypertension
Shunts
Surgery
Transplantation Surgery
Transplant Surgery
Honors: 

2020 New York Super Doctors

2020 Rising Star in Transplant Surgery, American Society of Transplant Surgery 2020

2019 Co-Chair, Surgical Committee of The Starzl Network for Excellence in Pediatric Transplantation

2018 Faculty Development Grant, American Society of Transplant Surgeons

2017 Nominated for Physician of the Year by Surgical Intensive Care Unit

2015 AASLD Career Development Award in Liver Transplantation

2013 Forde Award for Research, Columbia University

2013 Department of Surgery's Chairman's Research Award, Columbia University College of Physicians and Surgeons

2013 Louis V. Gerstner, Jr. Scholar – Research Award, Columbia University College of Physicians and Surgeons

2011 Blakemore Prize - Best Resident Research Award, Columbia University College of Physicians and Surgeons

2010 Administrative Chief Resident in General Surgery, Columbia University

2009 Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons

2008 American Society of Transplantation Young Investigator Award, Transplantation Biology Research Center, Harvard Medical School

2007 International Xenotransplantation Travel Grant, Transplantation Biology Research Center, Harvard Medical School

2005 American Society of Transplantation/JDRF Research Fellowship Award, Transplantation Biology Research Center, Harvard Medical School

2003 Alpha Omega Alpha, University of Missouri-Columbia School of Medicine

Interests: 
Allogeneic tolerance induction
Control of humoral rejection
Small for Size Syndrome after Living Donor Liver Transplantation
Use of Tregs to control natural antibody responses and facilitate xenogeneic bone marrow engraftment
Xenogeneic tolerance induction via mixed chimerism and thymus transplant
Lab Members: 
Nathaly Llore, MD, Postdoctoral Researcher
Paula Alonso-Guallart, DVM, Postdoctoral Researcher
Karina Bruestle, MD, Postdoctoral Researcher
Hiroshi Sakai, MD, Postdoctoral Researcher
Emily Lopes, Lab Technician
Genevieve Pierre, Lab Technician
Karl Erik Berglund, MD, Postdoctoral Researcher
Publications: 
Sakai H, Duggan E, Griesemer A. Size isn’t everything: “Small” LDLT grafts can have good outcomes. Transplantation 2020. Invited Commentary, In Press.
Bruestle K, Griesemer A. Pediatric Liver Transplantation in a Center That is Neither East Nor West. Annals of Surgery 2020. In Press.
Alonso-Gullart P, Llore N, Lopes E, Kofman S, Ho S, Stern J, Pierre G, Bruestle K, Tang, Q, Sykes M, Griesemer A. CD40L-stimulated B cells for ex vivo expansion of polyspecific nonhuman primate regulatory T cells for translational studies. Clinical and Experimental Immunology. 2020 In Revision.
Duggan EM, Griesemer A. Progress towards xenogeneic tolerance. Current Opinion in Organ Transplantation 2020. PMID: 32796179
Hozain AE, O’Neill JD, Pinezich MR, Tipograf U, Donocoff R, Cunningham KM, Tumen A, Fung K, Ukita R, Simpson M, Reimer JA, Ruiz EC, Queen D, Stokes JW, Cardwell NK, Talackine J, Snoeck H, Chen Y, Romanov, A, Marboe CC, Griesemer AD, Guenthart BA, Bacchetta M, Vunjak-Novakovic G. Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs. Nature Medicine. 2020 Jul;26(7):1102-1113. PMID: 32661401
Kato T, Hwang R, Liou P, Weiner J, Griesemer A, Samstein B, Halazun K, Mathur A, Schwartz G, Cherqui D, Emond J. Ex vivo resection and autotransplantation for conventionally unresectable tumors – an 11-year single center experience. Annals of Surgery. 2020. PMID: 32833756
Heinz N, Griesemer A, Kinney J, Vittorio J, Lagana S, Golder D, Velasco M, Kato T, Lobritto S, Martinez M. A case of infant with SARS-CoV-2 hepatitis early after liver transplantation. Pediatric Transplantation. 2020. PMID: 32559354, PMCID: PMC7323125
Lagana SM, De Michele S, Lee MJ, Emond JC, Griesemer AD, Tulin-Silver SA, Verna EC, Martinez M, Lefkowitch JH. COVID-19 Associated Hepatitis Complicating Recent Living Donor Liver Transplantation. Archives of Pathology and Laboratory Medicine. 2020 Apr 17. PMID: 32302212
Chaudhry S, Kato Y, Weiner J, Alonso-Guallart P, Baker S, Woodland DC, Lefkowitch JH, Duran-Struuck R, Sondermeijer HP, Zitsman J, Sears ML, Wu A, Karolewski B, Houck PJ, Martinez M, Kato T, Sykes M, Griesemer AD. In contrast to kidney, liver allograft tolerance is not achieved with a transient mixed chimerism regimen in nonhuman primates. Transplantation. 2020 Apr 6. Epub ahead of print. PMID: 32265416
Winer L, Vivero M, Scully B, Cortez A, Kassam A, Nowygrod R, Griesemer A, Emond JE, Quill-in R. Exploring medical students' perceptions of organ procurement: Need for a formalized medical student curriculum. Journal of Surgical Education. J Surg Educ. 2019 Nov 18. PMID: 31753606
Sell-berg F, Berglund D, Binder C, Hope J, Fontenot J, Griesemer A, Sykes M, Sachs DH, Berglund E. Pharmacokinetic and pharmacodynamic study of a clinically effective anti-CD2 monoclonal antibody. Scand J Immunol. 2019 Oct 20:e12839. PMID: 31630416
Berglund E, Alonso-Guallart P, Danton M, Sellberg F, Binder C, Fröbom R, Berglund D, Llore N, Sakai H, Iuga A, Ekanayake-Alper D, Reimann KA, Sachs DH, Sykes M, Griesemer A. Safety and pharmacodynamics of anti-CD2 monoclonal antibody treatment in cynomolgus macaques. Transpl Int. 2019 Sep 15. PMID: 31523849